Articles

Vitamin D deficiency and risk of cardiovascular diseases: a narrative review

Vitamin D, a fat-soluble prohormone, has wide-ranging roles in the regulation of many physiological processes through their interactions with the vitamin D receptors (VDR). It plays a major role in bones and c...

Authors: Babikir Kheiri, Ahmed Abdalla, Mohammed Osman, Sahar Ahmed, Mustafa Hassan and Ghassan Bachuwa

High out-of-clinic blood pressure is associated with adiposity indicators in leisure physical activity practitioners in Midwest Brazil

Several diseases, such as obesity, hypertension and type 2 diabetes are frequently associated with metabolic abnormalities, high costs of healthcare and morbi-mortality; thus the aim of this study was to inves...

Authors: Bruna M. Giglio, Renata C. Fernandes, Ana B. Marini, João F. Mota and Gustavo D. Pimentel

Knowledge, attitudes and practices of hypertensive patients towards prevention and early detection of chronic kidney disease: a cross sectional study from Palestine

Hypertension is the second most common cause of chronic kidney disease (CKD). Therefore, the aims of the study were to assess the knowledge, attitudes and practices (KAP) of hypertensive patients towards preve...

Authors: Hala H. Sa’adeh, Razan N. Darwazeh, Amani A. Khalil and Sa’ed H. Zyoud

Differences in self-reported weekend catch up sleep between children and adolescents with and without primary hypertension

The data on the association of sleep duration and blood pressure in the pediatric age group have been mixed and most studies have focused on weekday sleep duration. The purpose of this study was to compare the...

Authors: Neena Gupta, Louise Maranda and Rakesh Gupta

Analysis of cytomegalovirus-specific T-cell responses in patients with hypertension: comparison of assay methods and antigens

Recent studies suggest an association between cytomegalovirus (CMV) infection and hypertension. In the present study, we used a variety of antigens and different assay methods to investigate the relationship b...

Authors: Jong-Chan Youn, Jun Yong Kim, Min Kyung Jung, Hee Tae Yu, Su-Hyung Park, In-Cheol Kim, Sun Ki Lee, Suk-Won Choi, Seongwoo Han, Kyu-Hyung Ryu, Sungha Park and Eui-Cheol Shin

Chlorthalidone, not hydrochlorothiazide, is the right diuretic for comparison

We have read the study design “Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic pa...

Authors: Ravi Tejraj Mehta, Anil Pareek and Indranil Purkait

Neck circumference is independently associated with relative systemic hypertension in young adults with sickle cell anaemia

A seemingly interesting observation in patients with sickle cell anaemia (SCA) is that they usually have lower systemic blood pressures (BP) and insulin resistance than persons in the general population in spi...

Authors: Lawrence A. Olatunji, Olatunde P. Olabode, Olawale M. Akinlade, Abiola S. Babatunde, Victoria A. Olatunji and Ayodele O. Soladoye

Efficacy and safety of azilsartan medoxomil, an angiotensin receptor blocker, in Korean patients with essential hypertension

This was a phase 3, randomized, double-blind, placebo-controlled study.

Authors: Attila Juhasz, Jingtao Wu, Michie Hisada, Tomoka Tsukada and Myung Ho Jeong

Interaction between body mass index and serum uric acid in relation to blood pressure in community-dwelling Japanese men

Few data is available on the association between body mass index (BMI), serum uric acid (SUA) levels and blood pressure (BP) categories in the disease continuum, when efforts for its prevention may be applicable.

Authors: Ryuichi Kawamoto, Daisuke Ninomiya, Kensuke Senzaki and Teru Kumagi

Blood pressure control and its determinants among diabetes mellitus co-morbid hypertensive patients at Jimma University medical center, South West Ethiopia

Hypertension is the major contributor to cardiovascular diseases related morbidity and mortality. Blood pressure is not well controlled in the majority of patients with both diabetes and hypertension. The main...

Authors: Sintayehu Muleta, Tsegaye Melaku, Legese Chelkeba and Desta Assefa

Systolic time ratio measured by impedance cardiography accurately screens left ventricular diastolic dysfunction in patients with arterial hypertension

The use of impedance cardiography (ICG) may play a role in the assessment of cardiac effects of hypertension (HT), especially its hemodynamic features. Hypertensive heart disease involves structural changes an...

Authors: Rodrigo Nazário Leão, Pedro Marques Silva, Luísa Branco, Helena Fonseca, Bruno Bento, Marta Alves, Daniel Virella and Roberto Palma Reis

Blunted heart rate recovery is associated with coronary artery spasm in patients with suspected vasospastic angina

Autonomic nervous system activity has been shown to be altered in patients with vasospastic angina (VA). Heart rate recovery (HRR) is a simple, non-invasive measurement of autonomic nervous system dysfunction....

Authors: Hyunsu Kim, Sang-Hoon Cho, Kyoung-Im Cho, Bong-Joon Kim, Sung-Il Im and Jung-Ho Heo

Amlodipine Vs. hydrochlorothiazide: is there any disparity in its antihypertensive effect or not?

We have read the article “Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic paramet...

Authors: Venu Gopal Jonnalagadda, Kanchan Choudhary and Vijay Kranti Matety

Status of hypertension screening in the Korea National General Health Screening Program: a questionnaire survey on 210 screening centers in two metropolitan areas

The purpose of this survey was to evaluate the performance of hypertension screening in medical institutions conducting the national general health screening program of the Republic of Korea.

Authors: Seung Won Lee, Hae-Young Lee, Sang Hyun Ihm, Sung Ha Park, Tae Hyun Kim and Hyeon Chang Kim

Lifestyle modification practice and associated factors among diagnosed hypertensive patients in selected hospitals, South Ethiopia

Hypertension is one of the leading causes of disability and death in both developed and developing countries that need urgent strategies to implement interventions that control it. Appropriate lifestyle change...

Authors: Eyasu Siyum Buda, Lolemo Kelbiso Hanfore, Robera Olana Fite and Alula Seyum Buda

Severe carvedilol toxicity without overdose – caution in cirrhosis

Carvedilol is used in the management of hypertension, ischemic heart disease, heart failure and most recently, portal hypertension. It has been associated with improved outcomes regarding variceal bleeding, he...

Authors: Satish Maharaj, Karan Seegobin, Julio Perez-Downes, Belinda Bajric, Simone Chang and Pramod Reddy

The salt-taste threshold in untreated hypertensive patients

The salt-taste threshold can influence the salt appetite, and is thought to be another marker of sodium intake. Many studies have mentioned the relationship between the sodium intake and blood pressure (BP). T...

Authors: Chang-Yeon Kim, Mi-Kyung Ye and Young Soo Lee

Differences in left ventricular functional adaptation to arterial stiffness and neurohormonal activation in patients with hypertension: a study with two-dimensional layer-specific speckle tracking echocardiography

Arterial stiffness increases pressure load to the left ventricle (LV), leading to LV hypertrophy and subendocardial ischemia. Neurohormones stimulate myocardial fibrosis and LV dysfunction. We aimed to explore...

Authors: Darae Kim, Chi Young Shim, Geu-Ru Hong, Sungha Park, InJeong Cho, Hyuk-Jae Chang, Jong-Won Ha and Namsik Chung

Identifying treatment response to antihypertensives in patients with obesity-related hypertension

In patients with obesity-related hypertension (ORH), reaction to antihypertensive medication is likely influenced by patientcharacteristics.

Authors: Ilse M. Schrover, Jannick A. N. Dorresteijn, Jodine E. Smits, A. H. Jan Danser, Frank L. J. Visseren and Wilko Spiering

Clinical impact of skin autofluorescence on high-sensitivity troponin T in hypertensive patients

Recent studies have reported the importance of high-sensitivity troponin T (hs-cTnT) or skin autofluorescence (AF) as a cardiovascular risk factor. However, little is known about the relationship between these...

Authors: Takashi Hitsumoto

Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters in hypertensive patients: study design for a multicenter, double-blinded, active-controlled, phase 4, randomized trial

Hypertension is a risk factor for coronary heart disease and stroke, and is one of the leading causes of death. Although over a billion people are affected worldwide, only half of them receive adequate treatme...

Authors: Gyu Chul Oh, Hae-Young Lee, Wook Jin Chung, Ho-Joong Youn, Eun-Joo Cho, Ki-Chul Sung, Shung Chull Chae, Byung-Su Yoo, Chang Gyu Park, Soon Jun Hong, Young Kwon Kim, Taek-Jong Hong, Dong-Ju Choi, Min Su Hyun, Jong Won Ha, Young Jo Kim…

Internal validation of an automated system for brachial and femoral flow mediated dilation

Flow Mediated Dilation (FMD) has immense potential to become a clinical, non-invasive biomarker of endothelial function and nitric oxide bioavailability, which regulate vasomotor activity. Unfortunately, FMD a...

Authors: Brycen Ratcliffe, Robert Pawlak, Francisco Morales, Caleb Harrison and Alvaro N. Gurovich

A multicenter cohort study of primary hypertension in Korea: study design and interim analysis of the Korean registry of target organ damage in hypertension (KorHR)

The Korean Registry of Target Organ Damage in Hypertension aims to evaluate the clinical characteristics and prevalence of subclinical target organ damage in Korean hypertensive patients.

Authors: Suk-Won Choi, Seong Woo Han, Jong Sun Ok, Byung-Su Yoo, Mi-Seung Shin, Sung Ha Park and Kyu-Hyung Ryu

Effect of respiratory pattern on automated clinical blood pressure measurement: an observational study with normotensive subjects

It has been reported that deep breathing could reduce blood pressures (BP) in general. It is also known that BP is decreased during inhalation and increased during exhalation. Therefore, the measured BPs could...

Authors: Natalia Herakova, Nnenna Harmony Nzeribe Nwobodo, Ying Wang, Fei Chen and Dingchang Zheng

Determinants of uncontrolled hypertension among clients on anti-retroviral therapy in Kadoma City, Zimbabwe, 2016

Clients on anti-retroviral therapy (ART) are living longer and have risk of hypertension. Side effects of medicines and aging increase this risk. Hypertension prevalence among clients on ART in Kadoma City was...

Authors: Pamela Nyaradzai Magande, Daniel Chirundu, Notion Tafara Gombe, More Mungati and Mufuta Tshimanga

Pathophysiology of copeptin in kidney disease and hypertension

Copeptin is derived from the cleavage of the precursor of arginine vasopressin (AVP), produced in an equimolar ratio in hypothalamus and processed during axonal transport AVP is an unstable peptide and has a s...

Authors: Baris Afsar

Hypertensive response to exercise and exercise training in hypertension: odd couple no more

The diagnostic and prognostic implication of exaggerated blood pressure response to exercise has been controversial, with opinions ranging from a benign process to a harbinger of potential cardiovascular morbi...

Authors: Elisa Caldarone, Paolo Severi, Mario Lombardi, Stefania D’Emidio, Andrea Mazza, Maria Grazia Bendini and Massimo Leggio

Attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular disease in the general practice: results of the Italian hypertension and brain survey

The aim of this survey was to evaluate attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular diseases (CVD) in Italy.

Authors: Giuliano Tocci, Arrigo F. Cicero, Massimo Salvetti, Maria Beatrice Musumeci, Andrea Ferrucci, Claudio Borghi and Massimo Volpe

Systolic blood pressure but not electrocardiogram QRS duration is associated with heart rate variability (HRV): a cross-sectional study in rural Australian non-diabetics

A positive correlation between ECG derived QRS duration and heart rate variability (HRV) parameters had previously been reported in young healthy adults. We note this study used a narrow QRS duration range, an...

Authors: Yvonne Yin Leng Lee, Herbert F. Jelinek and Craig S. McLachlan

Revised definition of predicted left ventricular mass using ambulatory blood pressure in healthy Korean adults

Left ventricular hypertrophy is influenced by both hemodynamic and non-hemodynamic factors. Ambulatory blood pressure is correlated with left ventricular hypertrophy. We established the influences of hemodynam...

Authors: Bae Keun Kim, Enshi Xu, Bo Youl Choi, Yonggu Lee, Soon Gil Kim, Yukio Yamori and Jinho Shin

Carotid artery intima-media thickness and hypertensive heart disease: a short review

Sustained by its relative ease of assessment, carotid artery intima-media thickness (cIMT) has emerged as an important surrogate marker of target organ damage in hypertensive heart disease over the last three ...

Authors: Costan G. Magnussen

Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population

Angiotensinogen (AGT) enzyme comprises a vital module of RAAS system that effectively controls the blood pressure and related cardiovascular functions. Ample association studies have reported the importance of...

Authors: Pulakes Purkait, Kalpataru Halder, Sunil Thakur, Abhishikta Ghosh Roy, Pradip Raychaudhuri, Sandip Bhattacharya, B. N. Sarkar and J. M. Naidu

Office orthostatic blood pressure measurements and ambulatory blood pressure monitoring in the prediction of autonomic dysfunction

In this retrospective analysis we investigated the predictive performance of orthostatic hypotension (OH) and ambulatory blood pressure monitoring (ABP) to predict autonomic dysfunction.

Authors: Kawther F. Alquadan, Girish Singhania, Abhilash Koratala and Abutaleb A. Ejaz

The cardiovascular risk factors associated with the plaque pattern on coronary computed tomographic angiography in subjects for health check-up

Although it is known that coronary computed tomographic angiography (CCTA) offers highly negative predictive value to exclude obstructive coronary lesions, the plaque pattern on CCTA has not been fully underst...

Authors: Dong-Hyeon Lee, Ho-Joong Youn, Hae-Ok Jung, Kiyuk Chang, Yun-Seok Choi and Jung Im Jung

Comparison of endothelial function improvement estimated with reactive hyperemia index between ramipril and telmisartan in hypertensive patients

Endothelium has a function to regulate vascular tone by releasing mediators either vasodilating or vasoconstricting blood vessels. Endothelial dysfunction can be measured conveniently by Reactive Hyperemia Ind...

Authors: You-Jeong Ki, Jae-Bin Seo, Hack-Lyoung Kim, Woo-Hyun Lim, Hye Yeon Seo, Jin Yong Lee and Woo-Young Chung

Autonomic imbalance captures maternal and fetal circulatory response to pre-eclampsia

Pre-eclampsia (PE) is a gestational disease featured by hypertension, arterial systemic vasculopathy, multiple organ failure and fetal compromise.

Authors: Igor Lakhno

Association between central blood pressure, arterial stiffness, and mild cognitive impairment

To determine the relationship between central blood pressure (CBP) indices and mild cognitive impairment (MCI) in adults over the age of 50.

Authors: R. Suleman, R. Padwal, P. Hamilton, A. Senthilselvan and K. Alagiakrishnan

Effects of metabolic syndrome on aortic pulse wave velocity

The purpose of this study was to compare the value and evaluate the validity of non-invasive methods for the detection of vascular stiffness in never-treated individuals with metabolic syndrome (MetS).

Authors: Dong-Hyeon Lee, Ho-Joong Youn, Woo-Baek Chung, Yun-Seok Choi, Jong-Min Lee, Chul-Soo Park, Hae-Ok Jung, Hui-Kyung Jeon and Man-Young Lee

Systolic blood pressure values might further risk-stratify the adverse outcomes of LVH in older patients with chronic kidney disease

LVH is highly prevalent in patients with CKD and is independently associated with subsequent cardiovascular events.

Authors: Carlos R. Franco Palacios, Pankaj Goyal, Amanda M. Thompson and Brent Deschaine

Neuronal nitric oxide synthase in hypertension – an update

Hypertension is a prevalent condition worldwide and is the key risk factor for fatal cardiovascular complications, such as stroke, sudden cardiac death and heart failure. Reduced bioavailability of nitric oxid...

Authors: Yin Hua Zhang

Relationship between retinopathy and renal abnormalities in black hypertensive patients

Complications of hypertension are particularly common in people of African descent but previous reports had suggested rarity of hypertensive retinopathy in black Africans. We evaluated retinal changes among Ni...

Authors: A. B. Omotoso, P. M. Kolo, T. O. Olanrewaju, J. F. Owoeye, S. A. Biliaminu and V. A. Olatunji

The flavor and acceptability of six different potassium-enriched (sodium reduced) iodized salts: a single-blind, randomized, crossover design

Hypertension is a serious public health problem. Potassium-enriched salt is suggested as a tool for lowering blood pressure. However, its flavor and taste acceptability is essential for population-based salt r...

Authors: Akram Maleki, Ali Reza Soltanian, Fatemeh Zeraati, Vida Sheikh and Jalal Poorolajal

Hypertensive response to exercise: mechanisms and clinical implication

A hypertensive response to exercise (HRE) is frequently observed in individuals without hypertension or other cardiovascular disease. However, mechanisms and clinical implication of HRE is not fully elucidated...

Authors: Darae Kim and Jong-Won Ha

Prognostic value of systolic short-term blood pressure variability in systolic heart failure

Traditional cardiovascular risk factors in the general population are usually correlated to a better prognosis in patients with chronic heart failure (HF). Most of the studies show that blood pressure variabil...

Authors: Matthieu Berry, Olivier Lairez, Joelle Fourcade, Jérôme Roncalli, Didier Carrié, Atul Pathak, Bernard Chamontin and Michel Galinier

Clinical assessment of hypertension in children

The use of blood pressure measurements have become a routine part of physical exam for the evacuation of cardiovascular health adults and, more recently, children. The most widely used definition of hypertensi...

Authors: Nisarg Patel and Nicole Walker

Hypertensive crisis in children: an experience in a single tertiary care center in Korea

Hypertensive crisis is a medical emergency that can cause acute damage to multiple end-organs. However, relatively little is known on the etiology, treatment, and outcomes of hypertensive crisis in Korean chil...

Authors: Geum Hwa Lee, I Re Lee, Se Jin Park, Ji Hong Kim, Ji Young Oh and Jae Il Shin

Changes of blood pressure, abdominal visceral fat tissue and gene expressions in fetal programming induced rat model after amlodipine–losartan combination treatment

There are a number of complications that can occur if there is under-nutrition during pregnancy followed by a period of rapid catch-up growth, including a higher chance of adult obesity, insulin resistance and...

Authors: Ji Hyen Lee, Hyeryon Lee, Sang Mi Lee, Pil Je Kang, Kwan Chang Kim and Young Mi Hong

A review on prescribing patterns of antihypertensive drugs

Hypertension continues to be an important public health concern because of its associated morbidity, mortality and economic impact on the society. It is a significant risk factor for cardiovascular, cerebrovas...

Authors: Noah Jarari, Narasinga Rao, Jagannadha Rao Peela, Khaled A. Ellafi, Srikumar Shakila, Abdul R. Said, Nagaraja Kumari Nelapalli, Yupa Min, Kin Darli Tun, Syed Ibrahim Jamallulail, Avinash Kousik Rawal, Ranjani Ramanujam, Ramesh Naidu Yedla, Dhilip Kumar Kandregula, Anuradha Argi and Laxmi Teja Peela

The utility of biomarker risk prediction score in patients with chronic heart failure

Chronic heart failure (CHF) has been remained a leading cause of cardiovascular morbidity and mortaluty. The risk stratification of CHF individuals based on clinical criteria and biomarkers' models may improve...

Authors: Alexander E. Berezin, Alexander A. Kremzer, Yulia V. Martovitskaya, Tatyana A. Berezina and Tatyana A. Samura

Erratum to: Prevalence of resistant hypertension and associated factors for blood pressure control status using Korean ambulatory blood pressure monitoring registry data

Authors: Sung Il Choi, Soon Kil Kim, Sungha Park, Ju Han Kim, Sang Hyun Ihm, Gwang-il Kim, Woo Shik Kim, Wook Bum Pyun, Yu-Mi Kim and Jinho Shin