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  1. Research

    The salt-taste threshold in untreated hypertensive patients

    The salt-taste threshold can influence the salt appetite, and is thought to be another marker of sodium intake. Many studies have mentioned the relationship between the sodium intake and blood pressure (BP). T...

    Chang-Yeon Kim, Mi-Kyung Ye and Young Soo Lee

    Clinical Hypertension 2017 23:22

    Published on: 15 November 2017

  2. Research

    Differences in left ventricular functional adaptation to arterial stiffness and neurohormonal activation in patients with hypertension: a study with two-dimensional layer-specific speckle tracking echocardiography

    Arterial stiffness increases pressure load to the left ventricle (LV), leading to LV hypertrophy and subendocardial ischemia. Neurohormones stimulate myocardial fibrosis and LV dysfunction. We aimed to explore...

    Darae Kim, Chi Young Shim, Geu-Ru Hong, Sungha Park, InJeong Cho, Hyuk-Jae Chang, Jong-Won Ha and Namsik Chung

    Clinical Hypertension 2017 23:21

    Published on: 2 November 2017

  3. Research

    Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters in hypertensive patients: study design for a multicenter, double-blinded, active-controlled, phase 4, randomized trial

    Hypertension is a risk factor for coronary heart disease and stroke, and is one of the leading causes of death. Although over a billion people are affected worldwide, only half of them receive adequate treatme...

    Gyu Chul Oh, Hae-Young Lee, Wook Jin Chung, Ho-Joong Youn, Eun-Joo Cho, Ki-Chul Sung, Shung Chull Chae, Byung-Su Yoo, Chang Gyu Park, Soon Jun Hong, Young Kwon Kim, Taek-Jong Hong, Dong-Ju Choi, Min Su Hyun, Jong Won Ha, Young Jo Kim…

    Clinical Hypertension 2017 23:18

    Published on: 4 September 2017

  4. Research

    A multicenter cohort study of primary hypertension in Korea: study design and interim analysis of the Korean registry of target organ damage in hypertension (KorHR)

    The Korean Registry of Target Organ Damage in Hypertension aims to evaluate the clinical characteristics and prevalence of subclinical target organ damage in Korean hypertensive patients.

    Suk-Won Choi, Seong Woo Han, Jong Sun Ok, Byung-Su Yoo, Mi-Seung Shin, Sung Ha Park and Kyu-Hyung Ryu

    Clinical Hypertension 2017 23:16

    Published on: 2 August 2017

  5. Research

    Effect of respiratory pattern on automated clinical blood pressure measurement: an observational study with normotensive subjects

    It has been reported that deep breathing could reduce blood pressures (BP) in general. It is also known that BP is decreased during inhalation and increased during exhalation. Therefore, the measured BPs could...

    Natalia Herakova, Nnenna Harmony Nzeribe Nwobodo, Ying Wang, Fei Chen and Dingchang Zheng

    Clinical Hypertension 2017 23:15

    Published on: 18 July 2017

  6. Research

    Determinants of uncontrolled hypertension among clients on anti-retroviral therapy in Kadoma City, Zimbabwe, 2016

    Clients on anti-retroviral therapy (ART) are living longer and have risk of hypertension. Side effects of medicines and aging increase this risk. Hypertension prevalence among clients on ART in Kadoma City was...

    Pamela Nyaradzai Magande, Daniel Chirundu, Notion Tafara Gombe, More Mungati and Mufuta Tshimanga

    Clinical Hypertension 2017 23:14

    Published on: 4 July 2017

  7. Review

    Pathophysiology of copeptin in kidney disease and hypertension

    Copeptin is derived from the cleavage of the precursor of arginine vasopressin (AVP), produced in an equimolar ratio in hypothalamus and processed during axonal transport AVP is an unstable peptide and has a s...

    Baris Afsar

    Clinical Hypertension 2017 23:13

    Published on: 13 June 2017

  8. Letter to the Editor

    Hypertensive response to exercise and exercise training in hypertension: odd couple no more

    The diagnostic and prognostic implication of exaggerated blood pressure response to exercise has been controversial, with opinions ranging from a benign process to a harbinger of potential cardiovascular morbi...

    Elisa Caldarone, Paolo Severi, Mario Lombardi, Stefania D’Emidio, Andrea Mazza, Maria Grazia Bendini and Massimo Leggio

    Clinical Hypertension 2017 23:11

    Published on: 2 June 2017

  9. Research

    Attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular disease in the general practice: results of the Italian hypertension and brain survey

    The aim of this survey was to evaluate attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular diseases (CVD) in Italy.

    Giuliano Tocci, Arrigo F. Cicero, Massimo Salvetti, Maria Beatrice Musumeci, Andrea Ferrucci, Claudio Borghi and Massimo Volpe

    Clinical Hypertension 2017 23:10

    Published on: 15 May 2017

  10. Research

    Systolic blood pressure but not electrocardiogram QRS duration is associated with heart rate variability (HRV): a cross-sectional study in rural Australian non-diabetics

    A positive correlation between ECG derived QRS duration and heart rate variability (HRV) parameters had previously been reported in young healthy adults. We note this study used a narrow QRS duration range, an...

    Yvonne Yin Leng Lee, Herbert F. Jelinek and Craig S. McLachlan

    Clinical Hypertension 2017 23:9

    Published on: 2 May 2017

  11. Research

    Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population

    Angiotensinogen (AGT) enzyme comprises a vital module of RAAS system that effectively controls the blood pressure and related cardiovascular functions. Ample association studies have reported the importance of...

    Pulakes Purkait, Kalpataru Halder, Sunil Thakur, Abhishikta Ghosh Roy, Pradip Raychaudhuri, Sandip Bhattacharya, B. N. Sarkar and J. M. Naidu

    Clinical Hypertension 2017 23:12

    Published on: 29 March 2017

  12. Research

    The cardiovascular risk factors associated with the plaque pattern on coronary computed tomographic angiography in subjects for health check-up

    Although it is known that coronary computed tomographic angiography (CCTA) offers highly negative predictive value to exclude obstructive coronary lesions, the plaque pattern on CCTA has not been fully underst...

    Dong-Hyeon Lee, Ho-Joong Youn, Hae-Ok Jung, Kiyuk Chang, Yun-Seok Choi and Jung Im Jung

    Clinical Hypertension 2017 23:6

    Published on: 2 March 2017

  13. Research

    Comparison of endothelial function improvement estimated with reactive hyperemia index between ramipril and telmisartan in hypertensive patients

    Endothelium has a function to regulate vascular tone by releasing mediators either vasodilating or vasoconstricting blood vessels. Endothelial dysfunction can be measured conveniently by Reactive Hyperemia Ind...

    You-Jeong Ki, Jae-Bin Seo, Hack-Lyoung Kim, Woo-Hyun Lim, Hye Yeon Seo, Jin Yong Lee and Woo-Young Chung

    Clinical Hypertension 2017 23:4

    Published on: 15 February 2017

  14. Research

    Effects of metabolic syndrome on aortic pulse wave velocity

    The purpose of this study was to compare the value and evaluate the validity of non-invasive methods for the detection of vascular stiffness in never-treated individuals with metabolic syndrome (MetS).

    Dong-Hyeon Lee, Ho-Joong Youn, Woo-Baek Chung, Yun-Seok Choi, Jong-Min Lee, Chul-Soo Park, Hae-Ok Jung, Hui-Kyung Jeon and Man-Young Lee

    Clinical Hypertension 2017 23:1

    Published on: 6 January 2017

  15. Review

    Neuronal nitric oxide synthase in hypertension – an update

    Hypertension is a prevalent condition worldwide and is the key risk factor for fatal cardiovascular complications, such as stroke, sudden cardiac death and heart failure. Reduced bioavailability of nitric oxid...

    Yin Hua Zhang

    Clinical Hypertension 2016 22:20

    Published on: 3 November 2016

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