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Table 2 Characteristics of study patients according to drug adherence

From: The role of ambulatory blood pressure monitoring in enhancing medication adherence among patients with newly diagnosed hypertension: an analysis of the National Health Insurance cohort database

Characteristic

Poor adherence

(n = 98,307)

Good adherence

(n = 48,673)

P value

With ABPM

14,730 (15.02)

13,386 (27.50)

< 0.001

Age, years

54.59 ± 14.53

56.24 ± 12.11

< 0.001

  ~ 29

4,576 (4.67)

601 (1.23)

< 0.001

 30 ~ 39

9,288 (9.47)

3,088 (6.34)

 40 ~ 49

20,067 (20.47)

10,130 (20.81)

 50 ~ 59

29,893 (30.49)

16,436 (33.77)

 60 ~ 69

18,666 (19.04)

11,415 (23.45)

 70 ~ 79

10,999 (11.22)

5,601 (11.51)

 80 ~ 

4,548 (4.64)

1,402 (2.88)

Female sex

45,140 (46.04)

21,835 (44.86)

< 0.001

Comorbidities

 Diabetes mellitus

11,583 (11.81)

6,497 (13.35)

< 0.001

 Dyslipidemia

20,233 (20.43)

11,108 (22.82)

< 0.001

 Chronic kidney disease

226 (0.23)

105 (0.22)

0.614

 Atrial fibrillation

455 (0.46)

291 (0.60)

< 0.001

 Ischemic heart disease

3,811 (3.21)

1,585 (5.64)

0.001

 Myocardial infarction

183 (0.19)

127 (0.26)

0.004

 Heart failure

447 (0.46)

239 (0.49)

0.375

 Ischemic stroke

2,005 (2.05)

1,105 (2.27)

0.005

 Intracranial hemorrhage

242 (0.25)

124 (0.25)

0.817

 Transient ischemic attack

1,009 (1.03)

482 (0.99)

0.501

Concomitant medications

 Anti-platelets

5,100 (5.20)

2,991 (6.15)

< 0.001

 Anti-diabetics

5,617 (5.73)

3,302 (6.78)

< 0.001

 Statins

7,539 (7.69)

4,371 (8.98)

< 0.001

AHM number

1.82 ± 2.82

1.83 ± 2.25

0.539

 0 ~  < 1 pill

9,430 (9.62)

3,804 (7.82)

< 0.001

 1 pill

35,277 (35.98)

15,197 (31.22)

 1 ~  < 2 pills

29,120 (29.70)

17,570 (36.10)

 2 ~  < 3 pills

14,405 (14.69)

7,341 (15.08)

 3 ~  < 4 pills

4,198 (4.28)

1,946 (4.00)

 ≥ 4 pills

5,607 (5.72)

2,815 (5.78)

Daily dosing frequency of AHM

1.39 ± 0.80

1.28 ± 0.63

< 0.001

 ≤ 1 pill

52,889 (53.95)

29,692 (61.00)

< 0.001

 1 <  ~  < 2 pills

25,129 (25.63)

13,335 (27.40)

 ≥ 2 pills

20,019 (20.42)

5,646 (11.60)

  1. Numbers are expressed as mean ± standard deviation or n (%). ABPM, ambulatory blood pressure monitoring
  2. AHM anti-hypertensive medication