Characteristic | Poor adherence (n = 98,307) | Good adherence (n = 48,673) | P value |
---|---|---|---|
With ABPM | 14,730 (15.02) | 13,386 (27.50) | < 0.001 |
Age, years | 54.59 ± 14.53 | 56.24 ± 12.11 | < 0.001 |
~ 29 | 4,576 (4.67) | 601 (1.23) | < 0.001 |
30 ~ 39 | 9,288 (9.47) | 3,088 (6.34) | |
40 ~ 49 | 20,067 (20.47) | 10,130 (20.81) | |
50 ~ 59 | 29,893 (30.49) | 16,436 (33.77) | |
60 ~ 69 | 18,666 (19.04) | 11,415 (23.45) | |
70 ~ 79 | 10,999 (11.22) | 5,601 (11.51) | |
80 ~ | 4,548 (4.64) | 1,402 (2.88) | |
Female sex | 45,140 (46.04) | 21,835 (44.86) | < 0.001 |
Comorbidities | |||
Diabetes mellitus | 11,583 (11.81) | 6,497 (13.35) | < 0.001 |
Dyslipidemia | 20,233 (20.43) | 11,108 (22.82) | < 0.001 |
Chronic kidney disease | 226 (0.23) | 105 (0.22) | 0.614 |
Atrial fibrillation | 455 (0.46) | 291 (0.60) | < 0.001 |
Ischemic heart disease | 3,811 (3.21) | 1,585 (5.64) | 0.001 |
Myocardial infarction | 183 (0.19) | 127 (0.26) | 0.004 |
Heart failure | 447 (0.46) | 239 (0.49) | 0.375 |
Ischemic stroke | 2,005 (2.05) | 1,105 (2.27) | 0.005 |
Intracranial hemorrhage | 242 (0.25) | 124 (0.25) | 0.817 |
Transient ischemic attack | 1,009 (1.03) | 482 (0.99) | 0.501 |
Concomitant medications | |||
Anti-platelets | 5,100 (5.20) | 2,991 (6.15) | < 0.001 |
Anti-diabetics | 5,617 (5.73) | 3,302 (6.78) | < 0.001 |
Statins | 7,539 (7.69) | 4,371 (8.98) | < 0.001 |
AHM number | 1.82 ± 2.82 | 1.83 ± 2.25 | 0.539 |
0 ~ < 1 pill | 9,430 (9.62) | 3,804 (7.82) | < 0.001 |
1 pill | 35,277 (35.98) | 15,197 (31.22) | |
1 ~ < 2 pills | 29,120 (29.70) | 17,570 (36.10) | |
2 ~ < 3 pills | 14,405 (14.69) | 7,341 (15.08) | |
3 ~ < 4 pills | 4,198 (4.28) | 1,946 (4.00) | |
≥ 4 pills | 5,607 (5.72) | 2,815 (5.78) | |
Daily dosing frequency of AHM | 1.39 ± 0.80 | 1.28 ± 0.63 | < 0.001 |
≤ 1 pill | 52,889 (53.95) | 29,692 (61.00) | < 0.001 |
1 < ~ < 2 pills | 25,129 (25.63) | 13,335 (27.40) | |
≥ 2 pills | 20,019 (20.42) | 5,646 (11.60) |