Relationship between the methylenetetrahydrofolate reductase (MTHFR) rs1801133 SNP and serum homocysteine levels of Zhuang hypertensive patients in the central region of Guangxi

Table 2 Influencing factors of serum Hcy levels in the control and H-type hypertension groups

Variable	Standardized coefficient	P-value	95% Confidence interval
Control group
Creatinine (µmol/L)	0.165	0.032	0.004 to 0.085
LDL-C (mmol/L)	0.286	0.021	0.280 to 3.412
Ccr (ml/min)	–0.273	< 0.001	–0.116 to − 0.036
MTHFR rs1801133 genotype	0.258	0.013	0.095 to 0.190
H-type group
Creatinine (µmol/L)	0.184	0.002	0.019 to 0.083
Triglyceride(mmol/L)	0.167	0.001	0.272 to 1.036
LDL-C (mmol/L)	0.249	0.005	0.501 to 2.874
Ccr (ml/min)	–0.190	< 0.001	–0.092 to − 0.029
Glycosylated hemoglobin (%)	–0.234	< 0.001	–2.593 to − 0.890
MTHFR rs1801133 genotype	0.226	0.001	0.045 to 0.143

LDL-C, low-density lipoprotein cholesterol; Ccr, endogenous creatinine clearance rate; THFR, methylenetetrahydrofolate reductase

ISSN: 2056-5909