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Table 1 Comparison of general data between the control and total hypertension, H-type hypertension, and non–H-type hypertension groups

From: Relationship between the methylenetetrahydrofolate reductase (MTHFR) rs1801133 SNP and serum homocysteine levels of Zhuang hypertensive patients in the central region of Guangxi

Variable

Control

(n = 379)

Hypertension

P-value

  

All

(n = 606)

H-type

(n = 528)

Non–H-type

(n = 78)

P1

P2

P3

Sex

    

0.833

0.662

0.904

Male

114

186

162

24

   

Female

265

420

366

54

   

Age (yr)

55.96 ± 8.84

55.75 ± 9.94

56.06 ± 9.56

55.69 ± 12.08

0.433

0.094

0.204

Height (cm)

160.05 ± 6.53

160.12 ± 6.86

159.96 ± 6.70

161.19 ± 7.79

0.653

0.201

0.173

Weight (kg)

59.34 ± 8.92

61.32 ± 9.79

60.87 ± 8.67

64.39 ± 15.07

< 0.001

0.016

< 0.001

Waist circumference (cm)

81.81 ± 12.12

83.92 ± 10.64

83.94 ± 10.48

83.77 ± 11.76

0.004

0.908

0.193

Hip circumference (cm)

90.53 ± 13.07

92.28 ± 13.03

91.92 ± 12.50

94.69 ± 16.07

0.018

0.136

0.015

Heart rate (beats/min)

74.31 ± 10.14

77.03 ± 11.26

76.69 ± 11.43

79.31 ± 9.80

< 0.001

0.089

< 0.001

Systolic blood pressure (mmHg)

123.94 ± 10.33

158.23 ± 16.02

157.84 ± 15.01

160.89 ± 21.62

< 0.001

0.188

< 0.001

Diastolic blood pressure (mmHg)

72.94 ± 8.67

91.18 ± 12.81

90.71 ± 12.78

94.38 ± 12.62

< 0.001

0.038

< 0.001

Homocysteine (µmol/L)

11.97 ± 5.39

14.20 ± 5.78

15.08 ± 5.65

8.26 ± 1.65

< 0.001

< 0.001

< 0.001

Urea nitrogen (mmol/L)

5.54 ± 1.62

4.73 ± 1.15

4.85 ± 1.03

4.07 ± 1.20

0.289

< 0.001

< 0.001

Creatinine (µmol/L)

83.33 ± 18.46

82.40 ± 21.77

85.27 ± 15.35

64.39 ± 20.90

0.478

0.001

0.001

Uric acid (µmol/L)

381.55 ± 81.69

390.01 ± 58.98

381.36 ± 59.96

329.35 ± 78.20

0.035

0.016

0.366

Endogenous creatinine clearance rate (mL/min)

99.90 ± 14.47

99.36 ± 16.31

94.87 ± 11.44

115.85 ± 18.29

0.245

< 0.001

< 0.001

Blood glucose (mmol/L)

4.78 ± 0.64

4.99 ± 0.85

4.95 ± 0.67

5.41 ± 2.17

0.017

0.528

0.110

Glycosylated hemoglobin (%)

5.54 ± 0.46

5.56 ± 0.71

5.41 ± 0.53

5.96 ± 1.22

0.774

0.162

0.864

Total cholesterol (mmol/L)

5.27 ± 0.82

5.43 ± 0.81

5.51 ± 0.65

5.16 ± 1.03

0.204

0.006

0.084

Triglyceride (mmol/L)

1.56 ± 0.98

1.84 ± 1.15

2.03 ± 1.26

1.64 ± 1.04

0.001

0.203

0.536

High-density lipoprotein cholesterol (mmol/L)

1.56 ± 0.30

1.48 ± 0.37

1.52 ± 0.30

1.53 ± 0.45

< 0.001

0.267

0.003

Low-density lipoprotein cholesterol. (mmol/L)

3.45 ± 0.78

3.56 ± 0.97

3.79 ± 0.61

3.20 ± 1.04

0.024

< 0.001

0.015

Antihypertensive drugs

0

225 (37.13)

188 (35.61)

37 (47.44)a)

< 0.001

< 0.001

< 0.001

  1. Data are presented as number only, mean ± standard deviation, or number (%). P1 values are compared between the control and total hypertension groups, P2 values are compared between the control and H-type hypertension groups, and P3 values are compared between the control and non–H-type hypertension groups
  2. a)χ2 = 4.047, P = 0.043 in comparison with H-type hypertensive group