Table 2 Comparison among patients with and without neurological deterioration a)
Variable | Neurological deterioration (−) (n = 616) | Neurological deterioration (+) (n = 92) | P-value |
|---|---|---|---|
Age (yr) | 67.7 ± 13.2 | 71.2 ± 11.2 | 0.016* |
Female sex | 293 (47.6) | 54 (58.7) | 0.060** |
Hypertension | 396 (64.3) | 64 (69.6) | 0.383 |
Diabetes mellitus | 206 (33.4) | 33 (35.9) | 0.733 |
Current smoking | 177 (28.7) | 16 (17.4) | 0.031* |
Atrial fibrillation | 113 (18.3) | 29 (31.5) | 0.005* |
Previous stroke | 129 (20.9) | 23 (25.0) | 0.454 |
SBP (mmHg) | 146.3 ± 27.1 | 153.2 ± 25.7 | 0.023* |
Hematocrit | 40.4 ± 5.9 | 40.4 ± 5.0 | 0.954 |
Leukocytes (109/L) | 8.21 ± 4.43 | 8.51 ± 3.75 | 0.485 |
Fasting blood glucose (mmol/L) | 3.65 ± 1.59 | 3.70 ± 1.19 | 0.704 |
HbA1c (%) | 6.20 ± 1.42 | 6.07 ± 1.04 | 0.278 |
Total cholesterol (mmol/L) | 4.74 ± 1.30 | 4.67 ± 1.07 | 0.565 |
LDL cholesterol (mmol/L) | 2.78 ± 0.92 | 2.77 ± 0.84 | 0.898 |
hsCRP (mmol/L) | 0.22 ± 0.67 | 0.25 ± 0.85 | 0.725 |
Homocysteine (μmol/L) | 15.40 ± 6.92 | 14.16 ± 5.09 | 0.043* |
Basilar artery PI | 0.95 ± 0.22 | 1.02 ± 0.26 | 0.014* |
Right MCA PI (n = 474) | 0.92 ± 0.21 (n = 422) | 0.97 ± 0.27 (n = 52) | 0.285 |
Left MCA PI (n = 456) | 1.09 ± 3.70 (n = 406) | 0.96 ± 0.24 (n = 50) | 0.170 |
Cerebral microbleeds | 267 (43.3) | 45 (48.9) | 0.373 |
Old lacunes | 416 (67.5) | 61 (66.3) | 0.908 |
CAS | 3 (0–6) | 5 (2–8) | 0.002*** |
WMH lesion | 461 (74.8) | 79 (85.9) | 0.029* |
NIHSS score at admission | 2 (0–5) | 6 (3–9) | < 0.001*** |