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Table 1 Clinical characteristics of the study population according to BA PI

From: Increased pulsatility index of the basilar artery is a risk factor for neurological deterioration after stroke: a case control study

Characteristics

Group 1

(n = 178)a)

Group 2

(n = 192)b)

Group 3

(n = 219)c)

Group 4

(n = 119)d)

P-value

Age (yr)

59.7 ± 14.0

66.5 ± 12.0

72.0 ± 10.4

76.3 ± 8.7

< 0.001***

Female sex

73 (41.0)

90 (46.9)

119 (54.3)

65 (54.6)

0.031*

Neurological deterioration

19 (10.7)

20 (10.4)

28 (12.8)

25 (21.0)

0.033*

Hypertension

96 (53.9)

121 (63.0)

147 (67.1)

96 (80.7)

< 0.001***

Diabetes mellitus

39 (21.9)

64 (33.3)

87 (39.7)

49 (41.2)

0.001**

Current smoking

53 (29.8)

50 (26.0)

62 (28.3)

28 (23.5)

0.644

Atrial fibrillation

29 (16.3)

40 (20.8)

42 (19.2)

31 (26.1)

0.220

Previous stroke

40 (22.5)

37 (19.3)

44 (20.1)

31 (26.1)

0.497

SBP (mmHg)

144.8 ± 25.8

144.5 ± 26.6

150.4 ± 28.1

149.1 ± 26.9

0.074

Hematocrit

41.0 ± 6.3

40.8 ± 5.6

39.6 ± 5.5

40.0 ± 5.5

0.068

Leukocytes (109/L)

7.80 ± 2.83

8.62 ± 6.46

8.41 ± 3.24

8.04 ± 3.67

0.157

Fasting blood glucose (mmol/L)

3.40 ± 1.51

3.70 ± 1.45

3.71 ± 1.57

3.87 ± 1.67

0.065

HbA1c (%)

5.99 ± 1.35

6.07 ± 1.32

6.37 ± 1.43

6.31 ± 1.34

0.027*

Total cholesterol (mmol/L)

4.81 ± 1.26

4.67 ± 1.31

4.74 ± 1.25

4.67 ± 1.30

0.680

LDL cholesterol (mmol/L)

2.81 ± 0.89

2.77 ± 0.95

2.79 ± 0.89

2.75 ± 0.90

0.943

hsCRP (mmol/L)

0.17 ± 0.57

0.19 ± 0.57

0.22 ± 0.64

0.37 ± 1.06

0.278

Homocysteine (μmol/L)

14.94 ± 7.53

14.61 ± 6.28

15.19 ± 6.20

16.77 ± 6.89

0.051

Right MCA PI (n = 474)

0.75 ± 0.13 (n = 138)

0.87 ± 0.13 (n = 136)

1.02 ± 0.16 (n = 137)

1.23 ± 0.20 (n = 63)

< 0.001***

Left MCA PI (n = 456)

1.26 ± 6.32 (n = 138)

0.86 ± 0.11 (n = 127)

1.03 ± 0.16 (n = 133)

1.21 ± 0.21 (n = 58)

< 0.001***

Cerebral microbleeds

70 (39.3)

86 (44.8)

101 (46.1)

55 (46.2)

0.520

Old lacunes

104 (58.4)

121 (63.0)

162 (74.0)

90 (75.6)

0.001**

CAS

2 (0–5)

3 (0–6)

4 (1–7)

4 (2–6)

0.181

WMH lesion

97 (54.5)

148 (77.1)

190 (86.8)

105 (88.2)

< 0.001***

NIHSS score at admission

2 (0–5)

2 (0–5)

2 (1–6)

3 (1–7)

0.079

  1. Values are presented as means ± standard deviation, number (%), or median (interquartile range). Differences between groups were analyzed using the analysis of chi-square test and the one-way analysis of variance test. Kruskal-Wallis tests were used to compare the CAS between groups
  2. BA  Basilar artery, PI Pulsatility index, SBP Systolic blood pressure, HbA1c Hemoglobin A1c, LDL Low-density lipoprotein, hsCRP High sensitivity C-reactive protein, MCA Right middle cerebral artery, CAS Cerebral atherosclerosis score, WMH White matter hyperintensity, NIHSS National Institutes of Health Stroke Scale
  3. a) BA PI, 0.42–0.80; b) BA PI, 0.80–0.94; c) BA PI, 0.94–1.10; d) BA PI, 1.10–2.50
  4. *P < 0.05, **P < 0.01, ***P < 0.001