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Table 4 Mean values of central blood pressure measurements according to the presence of TOD

From: Associations between measurements of central blood pressure and target organ damage in high-risk patients

Variable

TOD (+)

TOD (–)

P-value

Obstructive CAD

(+) (n = 104)

(–) (n = 30)

 

CSBP, mmHg

139 ± 19

139 ± 18

0.881

CDBP, mmHg

75.4 ± 9.7

81.1 ± 9.7

0.007

CMAP, mmHg

96.8 ± 11.3

100.5 ± 11.3

0.115

CPP, mmHg

64.1 ± 17.1

56.0 ± 14.3

0.036

LVMI

> 115 g/m2 for male and > 95 g/m2 for female (n = 91)

≤ 115 g/m2 for male and ≤ 95 g/m2 for female (n = 31)

 

CSBP, mmHg

140 ± 20

138 ± 19

0.770

CDBP, mmHg

72.8 ± 9.9

77.2 ± 9.8

0.031

CMAP, mmHg

95.1 ± 10.7

97.7 ± 11.7

0.294

CPP, mmHg

68.1 ± 20.0

61.3 ± 15.4

0.041

RWT

> 0.42 (n = 24)

≤ 0.42 (n = 98)

 

CSBP, mmHg

142 ± 23

138 ± 18

0.311

CDBP, mmHg

76.0 ± 10.8

76.1 ± 9.8

0.976

CMAP, mmHg

98.2 ± 12.9

96.7 ± 11.1

0.565

CPP, mmHg

66.7 ± 21.0

61.9 ± 15.6

0.307

e′ velocity

< 7 cm/sec (n = 105)

≥ 7 cm/sec (n = 17)

 

CSBP, mmHg

140 ± 20

132 ± 14

0.113

CDBP, mmHg

75.6 ± 10.1

78.9 ± 8.6

0.216

CMAP, mmHg

97.1 ± 11.8

96.7 ± 9.7

0.888

CPP, mmHg

64.4 ± 17.1

53.1 ± 10.6

0.010

E/e′

> 15 (n = 25)

≤ 15 (n = 97)

 

CSBP, mmHg

143 ± 23

137 ± 18

0.173

CDBP, mmHg

73.8 ± 11.9

76.7 ± 9.4

0.192

CMAP, mmHg

97.1 ± 14.5

97.0 ± 10.6

0.967

CPP, mmHg

70.1 ± 16.5

60.0 ± 16.5

0.015

eGFR

< 60 mL/min/1.73 m2 (n = 27)

≥ 60 mL/min/1.73 m2 (n = 107)

 

CSBP, mmHg

143 ± 19

138 ± 19

0.330

CDBP, mmHg

74.5 ± 8.6

77.3 ± 10.2

0.188

CMAP, mmHg

97.1 ± 10.9

97.8 ± 11.5

0.791

CPP, mmHg

67.8 ± 16.7

61.4 ± 16.5

0.085

ACR

> 30 mg/g (n = 43)

≤ 30 mg/g (n = 78)

 

CSBP, mmHg

144 ± 19

136 ± 18

0.034

CDBP, mmHg

76.2 ± 10.0

76.5 ± 9.7

0.877

CMAP, mmHg

98.7 ± 11.2

96.6 ± 11.0

0.303

CPP, mmHg

67.8 ± 18.5

60.1 ± 14.8

0.015

baPWV

> 1,600 cm/sec (n = 57)

≤ 1,600 cm/sec (n = 77)

 

CSBP, mmHg

145 ± 19

135 ± 18

0.003

CDBP, mmHg

77.3 ± 10.5

76.3 ± 9.6

0.578

CMAP, mmHg

99.9 ± 11.9

95.9 ± 10.7

0.043

CPP, mmHg

68.0 ± 16.6

58.8 ± 15.7

0.001

ABI

< 0.9 (n = 9)

≥ 0.9 (n = 125)

 

CSBP, mmHg

145 ± 24

139 ± 19

0.353

CDBP, mmHg

67.6 ± 11.4

77.4 ± 9.6

0.004

CMAP, mmHg

93.6 ± 14.6

97.9 ± 11.1

0.277

CPP, mmHg

77.8 ± 17.3

61.7 ± 16.2

0.005

  1. TOD, target organ damage; CAD, coronary artery disease; CSBP, central systolic blood pressure; CDBP, central diastolic blood pressure; CMAP, central mean arterial pressure; CPP, central pulse pressure; LVMI, left ventricular mass index; RWT, relative wall thickness; eGFR, estimated glomerular filtration rate; ACR, albumin-creatinine ratio; baPWV, brachial-ankle pulse wave velocity; ABI, ankle-brachial index