Table 5 Sub-analysis of deep breathing test results with exclusion of patients on beta-adrenergicblockers
BP response to the deep breathing test | White-coat effect | p value | |
Present | Absent | ||
A. Patients not on beta-adrenergic blockers (N = 140) | n = 94 | n = 46 | |
Mean SBP drop (mmHg) | 15.7 (SD 11.5) | 12.8 (SD 11.0) | 0.149 |
Mean DBP drop (mmHg) | 4.5 (SD 5.1) | 3.9 (SD 4.3) | 0.465 |
B. Patients not on beta-adrenergic blockers and with different clinic SBP cut-off before DBT | |||
(i) SBP ≥ 145 mmHg (N = 92) | n = 58 | n = 34 | |
Mean SBP drop (mmHg) | 19.8 (SD 12.1) | 14.5 (SD 11.5) | *0.043 |
Mean DBP drop (mmHg) | 4.9 (SD 5.2) | 4.1 (SD 4.3) | 0.449 |
(ii) SBP ≥ 155 mmHg (N = 58) | n = 38 | n = 20 | |
Mean SBP drop (mmHg) | 22.0 (SD 13.4) | 15.1 (SD 13.7) | 0.068 |
Mean DBP drop (mmHg) | 4.9 (SD 6.0) | 4.6 (SD 4.4) | 0.847 |
(iii) SBP ≥ 165 mmHg (N = 33) | n = 22 | n = 11 | |
Mean SBP drop (mmHg) | 25.6 (SD 13.1) | 14.6 (SD 14.3) | *0.035 |
Mean DBP drop (mmHg) | 6.1 (SD 5.6) | 3.8 (SD 3.6) | 0.232 |
Deep breathing test operating characteristics | Area under ROC curve | 95% confidence interval (CI) | p value |
A. Patients not on beta-adrenergic blockers (N = 140) | |||
SBP change | 0.56 | 0.46–0.66 | 0.288 |
DBP change | 0.53 | 0.43–0.63 | 0.554 |
B. Patients not on beta-adrenergic blockers and with different clinic SBP cut-off before DBT | |||
(i) SBP ≥ 145 mmHg (N = 92) | |||
SBP change | 0.62 | 0.50–0.73 | 0.066 |
DBP change | 0.54 | 0.41–0.66 | 0.580 |
(ii) SBP ≥ 155 mmHg (N = 58) | |||
SBP change | 0.64 | 0.49–0.78 | 0.094 |
DBP change | 0.51 | 0.35–0.66 | 0.948 |
(iii) SBP ≥ 165 mmHg (N = 33) | |||
SBP change | 0.72 | 0.53–0.91 | *0.040 |
DBP change | 0.62 | 0.42–0.82 | 0.260 |