Interaction between body mass index and serum uric acid in relation to blood pressure in community-dwelling Japanese men

Table 1 Characteristics of participants categorized by body mass index

	Body mass index category (kg/m²)
Characteristics N = 817	< 21.0	21.0-24.9	≥25.0	P-value
Characteristics N = 817	N = 216	N = 439	N = 162	P-value
Age (years)	67 ± 9	67 ± 9	63 ± 9	< 0.001
Body mass index (kg/m²)	19.5 ± 1.1	23.0 ± 1.1	27.0 ± 2.0	< 0.001
Alcohol consumption^a (%)	37.0/20.8/9.3/32.9	42.6/21.9/9.1/26.4	34.6/30.2/7.4/27.8	0.157
Smoking status^b (%)	25.5/30.6/25.9/18.1	25.1/27.6/26.4/21.0	23.5/28.4/24.7/23.5	0.910
History of CVD, N (%)	16 (7.4)	41 (9.3)	11 (6.8)	0.514
Systolic blood pressure (mmHg)	132 ± 21	136 ± 19	142 ± 18	< 0.001
Diastolic blood pressure (mmHg)	79 ± 11	82 ± 10	85 ± 11	< 0.001
Triglycerides (mg/dL)	79 (59-101)	95 (72-141)	119 (81-161)	< 0.001
HDL cholesterol (mg/dL)	67 ± 17	58 ± 15	53 ± 13	< 0.001
LDL cholesterol (mg/dL)	103 ± 28	114 ± 30	115 ± 33	< 0.001
Antilipidemic medication, N (%)	3 (1.4)	25 (5.7)	9 (5.6)	0.035
Fasting plasma glucose (mg/dL)	98 (91-114)	102 (93-117)	103 (94-120)	0.042
Antiidiabetic medication, N (%)	6 (2.8)	28 (6.4)	8 (4.9)	0.145
Serum uric acid (mg/dL)	5.3 ± 1.2	5.7 ± 1.3	5.9 ± 1.2	< 0.001
eGFR (ml/min./1.73m²)	79.8 ± 13.9	77.0 ± 14.3	78.6 ± 15.3	0.051
Aspartate transaminase (IU/L)	17 (14-23)	19 (15-25)	23 (17-32)	< 0.001
γ-glutamyl transpeptidase (IU/L)	29 (20-43)	30 (22-49)	44 (28-69)	< 0.001

Data for triglycerides, fasting plasma glucose, aspartate transaminase, and γ-glutamyl transpeptidase were skewed and are presented as median (interquartile range) values, and were log-transformed for analysis. P-value: Student’s t-test for continuous variables or the χ² -test for categorical variables. Bolded numbers indicate significance
CVD cardiovascular disease, HDL high-density lipoprotein, LDL low-density lipoprotein, eGFR estimated glomerular filtration rate. Data presented are mean ± standard deviation
^aDaily alcohol consumption was measured using the Japanese liquor unit in which a unit corresponds to 22.9 g of ethanol, and the participants were classified into never, occasional, light daily (< 2 unit/day), and heavy daily drinkers (≥ 2 unit/day)
^bSmoking status [never-smoker, past-smoker, light smoker (< 30 pack · year), and heavy smoker (≥ 30 pack · year)]

ISSN: 2056-5909