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Table 3 Changes of serum lipid profile in fetal programming model after amlodipine-losartan combination treatment

From: Changes of blood pressure, abdominal visceral fat tissue and gene expressions in fetal programming induced rat model after amlodipine–losartan combination treatment

Week

 

Blood sugar (mg/dL)

TG (mg/dL)

TC (mg/dL)

HDL-C (mg/dL)

LDL-C (mg/dL)

4

C

288.50 ± 142.13

107.50 ± 62.98

84.33 ± 3.06

65.33 ± 11.93

18.00 ± 6.08

FR

237.00 ± 108.43

142.00 ± 47.76

82.67 ± 2.52

66.67 ± 0.87

16.00 ± 4.58

CX

205.00 ± 0.00

83.00 ± 2.83

76.50 ± 2.12

65.50 ± 0.72

18.00 ± 0.00

8

C

202.00 ± 14.72

45.75 ± 14.24

43.00 ± 6.78

40.50 ± 6.24

4.50 ± 1.00

FR

207.50 ± 58.34

145.50 ± 26.80*

62.75 ± 8.34

56.75 ± 0.85

7.50 ± 1.73

CX

263.00 ± 25.87

105.50 ± 28.63

62.75 ± 7.04

57.50 ± 5.45

9.25 ± 1.89

12

C

127.75 ± 10.21

20.25 ± 10.31

42.25 ± 3.40

42.25 ± 2.99

5.75 ± 1.26

FR

101.00 ± 18.17

38.25 ± 7.50*

41.50 ± 7.59

42.00 ± 6.68

5.00 ± 2.16

CX

165.00 ± 94.69

30.00 ± 8.54

37.25 ± 22.51

37.00 ± 14.72

4.25 ± 3.86

16

C

169.33 ± 3.33

62.50 ± 14.50

60.50 ± 12.82

52.00 ± 10.39

4.67 ± 0.47

FR

189.50 ± 11.32

81.50 ± 0.32

54.25 ± 6.54

48.50 ± 12.84

5.00 ± 2.74

CX

191.67 ± 39.14

86.25 ± 32.93

54.50 ± 7.09

445.75 ± 4.44

5.00 ± 0.82

20

C

141.17 ± 36.99

33.20 ± 13.31

48.50 ± 10.88

45.17 ± 9.70

5.33 ± 2.42

FR

195.00 ± 22.58

76.80 ± 13.03*

63.71 ± 17.74

56.71 ± 16.54

6.17 ± 3.29

CX

181.00 ± 19.61

42.75 ± 10.34†

68.00 ± 24.99

63.40 ± 2.48

8.20 ± 3.49

  1. C control, FR food restriction, CX amlodipine losartan-combination, TG triglyceride, TC total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol
  2. *C group vs FR group, p <0.05, † FR group vs CX group, p <0.05