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Figure 4 | Clinical Hypertension

Figure 4

From: Angiotensin II induces endoplasmic reticulum stress in podocyte, which would be further augmented by PI3-kinase inhibition

Figure 4

Schematic view of ER stress pathway induced by Ang II in podocyte. Ang II could induce podocyte ER stress of PERK-eIF2α-ATF4 axis via PI3-kinase pathway. Arrows mean induction or augmentation. Ang II, angiotensin II; AT1R, angiotensin II type 1 receptor; ATF6, activating transcription factor 6; Bip, binding immunoglobulin protein; eIF2α, eukaryotic translation initiation factor 2cme; ER, endoplasmic reticulum; PERK, PKR-like ER kinase.

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Clinical Hypertension

ISSN: 2056-5909

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