Figure 3
From: Depressor action and vasorelaxation of methylene chloride fraction extracted from Rubus coreanum
(A) Influence of methylene chloride (CH 2 Cl 2 ) fraction plus N ω-nitro-L-arginine methyl ester hydrochloride (L-NAME) on the contractile responses evoked by phenylephrine (PE) and high potassium (KCl) and (B) the typical tracing showing the effect of CH 2 Cl 2 fraction plus L-NAME on ( upper panel ) PE- and ( lower panel ) high potassium-induced contractile response in the isolated rat aortic strips. Statistical difference was obtained by comparing the control with the CH2Cl2 fraction-pretreated group or CH2Cl2 fraction (400 μg/mL) plus L-NAME (300 μM). Other methods are the same as in Figure 2. *p < 0.05. **p < 0.01. (A) Left: PE-induced contractile response (control); middle: PE-induced contractile response in the presence of CH2Cl2 fraction (400 μg/mL); right: PE-induced contractile response in the presence of CH2Cl2 fraction (400 μg/mL) plus L-NAME (300 μM). (B) Left: KCl-induced contractile response (control); middle: KCl-induced contractile response in the presence of CH2Cl2 fraction (400 μg/mL); right: KCl-induced contractile response in the presence of CH2Cl2 fraction (400 μg/mL) plus L-NAME (300 μM).