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Fig. 1 | Clinical Hypertension

Fig. 1

From: Therapeutic roles of thiazides and loop diuretics in blood pressure control and renal protection against chronic kidney disease

Fig. 1

Schematic view of volume overload-induced hypertension in chronic kidney disease. Reduced glomerular filtration rate in chronic kidney disease eventually produces sodium retention and a fall in plasma renin level with minimal dependence of systemic angiotensin II, causing volume expansion and subsequent increased arterial pressure. In this situation, blockades of renin-angiotensin system are less effective in controlling systemic blood pressure

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