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Table 3 Odds ratios for hypertension according to δ13C, δ15N tertiles in 313 subjects without antihypertensive medication

From: The association between carbon and nitrogen stable isotope ratios of human hair and hypertension

Variable

Odds ratio (95% confidence interval)

Terrtile 1

Terrtile 2

Terrtile 3

P for trend

per 1‰ increase

δ13C, ‰ vs. PDB

<−20.71

−20.71 to −19.99

≥ − 19.98

–

–

 Hypertension

40 (29.4)

44 (33.6)

41 (32.8)

–

–

  Model 1

1.00

0.98 (0.53–1.84)

1.21 (0.61–2.38)

0.583

1.24 (0.89–1.73)

  Model 2

1.00

0.98 (0.52–1.83)

1.20 (0.61–2.36)

0.602

1.24 (0.89–1.73)

  Model 3

1.00

0.94 (0.50–1.77)

1.17 (0.59–2.34)

0.643

1.23 (0.88–1.73)

  Model 4

1.00

0.94 (0.49–1.77)

1.10 (0.54–2.26)

0.788

1.22 (0.86–1.72)

  Model 5

1.00

0.93 (0.49–1.76)

1.12 (0.54–2.29)

0.769

1.22 (0.86–1.73)

δ15N, ‰ vs. air

< 11.18

11.18 to 11.85

≥11.86

–

–

 Hypertension

35 (27.6)

43 (33.3)

47 (34.6)

–

–

  Model 1

1.00

1.55 (0.81–2.95)

2.31 (1.13–4.74)

0.022

1.57 (1.08–2.28)

  Model 2

1.00

1.57 (0.82–3.00)

2.32 (1.13–4.76)

0.021

1.56 (1.07–2.28)

  Model 3

1.00

1.61 (0.84–3.11)

2.33 (1.12–4.85)

0.024

1.61 (1.10–2.37)

  Model 4

1.00

1.54 (0.79–3.01)

2.28 (1.09–4.80)

0.029

1.58 (1.07–2.33)

  Model 5

1.00

1.50 (0.77–2.94)

2.19 (1.03–4.65)

0.040

1.55 (1.04–2.30)

  1. Model 1, adjusted for age, sex; Model 2, model 1 + additionally adjusted for total energy intake, dietary sodium intake; Model 3, model 2 + additionally adjusted for fasting glucose, triglyceride, high-density lipoprotein cholesterol; Model 4, model 3 + additionally adjusted for smoking, alcohol consumption, regular exercise; Model 5, model 4 + additionally adjusted for waist circumference; PDB, Pee Dee Belemnite