Association of the magnitude of the difference in blood pressure between office and ambulatory measurements with blood pressure variability in untreated individuals

Table 6 Distribution of systolic blood pressure difference and systolic blood pressure variability among systolic hypertension phenotypes

	Systolic normotension	White-coat systolic hypertension	Masked systolic hypertension	Sustained systolic hypertension	p*
n	91	31	54	120
SBP difference
ME > -5 mmHg, n (%)	8 (8.8)	0 (0.0)	37 (68.5)	25 (20.8)
ME -5 to < 0 mmHg, n (%)	13 (22)	0 (0.0)	11 (20.4)	28 (23.3)
Ref 0 to < 5 mmHg, n (%)	22 (24.2)	0 (0.0)	6 (11.1)	22 (18.3)
WE 5 to < 10 mmHg, n (%)	20 (22.0)	5 (16.1)	0 (0.0)	28 (23.3)
WE ≥ 10 mmHg, n (%)	28 (30.8)	26 (83.9)	0 (0.0)	17 (14.2)
SBP variability
SD of 24-h SBP, mmHg	12.9 ± 3.2	13.9 ± 4.0	16.2 ± 3.8	15.9 ± 4.8	0.156
SD of daytime SBP, mmHg	11.6 ± 3.8	13.4 ± 4.7	13.6 ± 3.8	14.0 ± 5.2	0.283
SD of nighttime SBP, mmHg	10.0 ± 4.5	9.9 ± 3.8	11.6 ± 4.0	11.9 ± 4.1	0.763
cv of 24-h SBP, %	10.4 ± 2.6	11.2 ± 3.2	11.8 ± 2.6	11.2 ± 3.3	0.107
cv of daytime SBP, %	9.2 ± 3.0	10.5 ± 3.6	9.4 ± 2.5	9.5 ± 3.4	0.278
cv of nighttime SBP, %	8.6 ± 3.7	8.6 ± 3.4	9.2 ± 2.9	9.0 ± 3.0	0.773
ARV of 24-h SBP, mmHg	10.4 ± 2.8	10.6 ± 3.4	11.4 ± 3.3	11.9 ± 4.1	0.617

Systolic hypertension phenotypes were classified into systolic normotension (office systolic and daytime ambulatory systolic normotension), white-coat systolic hypertension (office systolic hypertension but daytime ambulatory systolic normotension), masked systolic hypertension (office systolic normotension but daytime ambulatory systolic hypertension) and sustained systolic hypertension (office systolic and daytime ambulatory systolic hypertension)
Systolic blood pressure difference was calculated by subtracting ambulatory daytime SBP from office SBP
^*p-value by ANCOVA adjusted with age, sex, presence of diabetes and BP
SD Standard deviation, cv Coefficient of variation, SBP Systolic blood pressure, ARV Average real variability

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