Skip to main content

Table 2 Antihypertensive drugs used to control blood pressure for patient with very severe acute hypertension in ED

From: Clinical characteristics and prognosis of patients with very severe acute hypertension visiting the emergency department

 

All patients

(n = 1,391)

Patients with HMOD

(n = 547)

Patients without HMOD

(n = 844)

P value

Oral antihypertensive drugs

268 (19.3)

106 (19.4)

162 (19.2)

0.932

  Calcium antagonistsa

170 (12.2)

38 (6.9)

132 (15.6)

 < 0.001

  Beta-blockerb

62 (4.5)

31 (5.7)

31 (3.7)

0.078

  Renin-angiotensin system inhibitorc

22 (1.6)

13 (2.4)

9 (1.1)

0.056

  Nitroglycerin

73 (5.2)

54 (9.9)

19 (2.3)

 < 0.001

Intravenous antihypertensive drugs

619 (44.5)

432 (79.0)

187 (22.2)

 < 0.001

  Nicardipine

453 (32.6)

297 (54.3)

156 (18.5)

 < 0.001

  Labetalol

35 (2.5)

28 (5.1)

7 (0.8)

 < 0.001

  Esmolol

14 (1.0)

12 (2.2)

2 (0.2)

 < 0.001

  Nitroglycerin

211 (15.2)

173 (31.6)

38 (4.5)

 < 0.001

Cessation due to iatrogenic hypotension

71 (5.1)

41 (7.5)

30 (3.6)

0.048

  1. HMOD hypertension-mediated organ damage
  2. aCalcium antagonists included amlodipine and nifedipine
  3. bBeta-blocker included carvedilol, nebivolol, propranolol, atenolol, and bisoprolol
  4. cRenin-angiotensin system inhibitor included perindopril, candesartan, losartan, and fimasartan