Table 1 Baseline characteristics according to serum uric acid level
Variable | Total (n = 4,592) | Tertile 1 (n = 1,436) | Tertile 2 (n = 1,548) | Tertile 3 (n = 1,608) | P-valuea) |
|---|---|---|---|---|---|
Male sex | 1,733 (37.7) | 564 (39.3) | 550 (35.5) | 619 (38.5) | 0.08 |
Age (yr) | 60.1 ± 9.5 | 60.6 ± 9.6 | 59.3 ± 9.5 | 60.3 ± 9.4 | < 0.05 |
40–64 | 2,926 (63.7) | 864 (60.2) | 1,044 (67.4) | 1,018 (63.3) | |
> 65 | 1,666 (36.3) | 572 (39.8) | 504 (32.6) | 590 (36.7) | |
Smoking status | < 0.05 | ||||
Non-smoker | 2,401 (67.5) | 771 (67.1) | 844 (70.6) | 786 (65.0) | |
Ex-smoker | 578 (16.3) | 182 (15.8) | 193 (16.1) | 203 (16.8) | |
Current smoker | 576 (16.2) | 197 (17.1) | 159 (13.3) | 220 (18.2) | |
Drinking status | < 0.05 | ||||
Non-drinker | 2,409 (52.5) | 798 (55.6) | 830 (53.6) | 781 (48.6) | |
Ex-drinker | 294 (6.4) | 90 (6.3) | 90 (5.8) | 114 (7.1) | |
Current drinker | 1,886 (41.1) | 547 (38.1) | 628 (40.6) | 711 (44.3) | |
Height (cm) | 1,57.6 ± 8.3 | 157.3 ± 8.4 | 157.5 ± 8.3 | 157.9 ± 8.3 | 0.15 |
Weight (kg) | 59.7 ± 9.7 | 57.7 ± 9.2 | 59.4 ± 9.5 | 61.7 ± 10.0 | < 0.05 |
Body mass index (kg/m2) | 24.0 ± 3.0 | 23.3 ± 3.0 | 23.9 ± 2.9 | 24.7 ± 3.0 | < 0.05 |
Systolic blood pressure (mmHg) | 116.5 ± 11.6 | 116.0 ± 11.8 | 116.0 ± 11.5 | 117.4 ± 11.4 | < 0.05 |
Diastolic blood pressure (mmHg) | 74.6 ± 7.9 | 73.9 ± 8.1 | 74.6 ± 8.0 | 75.1 ± 7.6 | < 0.05 |
Fasting blood glucose (mg/dL) | 98.9 ± 23.5 | 100.6 ± 31.1 | 97.7 ± 19.9 | 98.5 ± 18.1 | < 0.05 |
eGFR (mL/min/1.73 m2) | 76.4 ± 11.3 | 79.4 ± 11.2 | 77.1 ± 10.3 | 73.0 ± 11.5 | < 0.05 |
Total cholesterol (mg/dL) | 197.4 ± 35.7 | 193.2 ± 35.1 | 196.0 ± 34.8 | 202.5 ± 36.4 | < 0.05 |
High-density lipoprotein (mg/dL) | 45.3 ± 10.8 | 46.6 ± 10.8 | 45.6 ± 10.9 | 43.9 ± 10.6 | < 0.05 |
Low density lipoprotein (mg/dL) | 124.0 ± 32.9 | 121.8 ± 31.6 | 123.4 ± 31.7 | 126.5 ± 34.9 | < 0.05 |
Triglyceride (mg/dL) | 140.5 ± 87.2 | 124.0 ± 69.5 | 134.8 ± 87.2 | 160.6 ± 97.0 | < 0.05 |
Diabetes mellitus | 438 (9.5) | 161 (11.2) | 123 (8.0) | 154 (9.6) | < 0.05 |
Dyslipidemia | 2,988 (65.1) | 835 (58.2) | 958 (61.9) | 1,195 (74.3) | < 0.05 |
Serum uric acid (mg/dL) | 4.8 ± 1.3 | 3.6 ± 0.7 | 4.6 ± 0.7 | 6.0 ± 1.2 | < 0.05 |
Hyperuricemia | 418 (9.1) | 418 (26.0) | < 0.05 |