Fig. 1

Individualized algorithm for target blood pressure (BP) according to different tolerability profiles in patients with multiple comorbidities. ASCVD, atherosclerotic cardiovascular diseases; CKD, chronic kidney diseases; e.g., for example; LAD, large artery disease. a)Grade of recommendation: IIa, should be considered in favor of usefulness/efficacy; b)IIb, may be considered with less-well established efficacy; c)III, not recommended