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Table 3 Associations of genetic and allelic frequencies of + 5665 G/T polymorphism with hypertension

From: Associations of + 138 Ins/del A and + 5665 G/T polymorphisms of endothelin-1 gene with hypertension in Burmese people in Magway, Myanmar

Model

Hypertensive patient (n = 60)

Control group (n = 60)

OR

95% CI

P-value

Genotypic model

GG

22 (36.67)

23 (38.33)

Reference

-

-

GT

27 (45.00)

30 (50.00)

0.941

0.430–2.057

0.999

TT

11 (18.33)

7 (11.67)

1.643

0.540–5.002

0.389

Dominant model

GG

22 (36.67)

23 (38.33)

1.074

0.513–2.249

0.861

GT + TT

38 (63.33)

37 (61.67)

Recessive model

GG + GT

49 (81.67)

53 (88.33)

1.700

0.610–4.733

0.315

TT

11 (18.33)

7 (11.67)

Allelic model

G

71 (59.17)

76 (63.33)

1.192

0.709–2.005

0.518

T

49 (40.83)

44 (36.67)

  1. Data are presented as number (%) unless otherwise specified
  2. G/T guanine-to-thymine, OR odds ratio, CI confidence interval