Associations of + 138 Ins/del A and + 5665 G/T polymorphisms of endothelin-1 gene with hypertension in Burmese people in Magway, Myanmar

Table 2 Associations of genetic and allelic frequencies of + 138 Ins/del A polymorphism with hypertension

Model		Hypertensive patient (n = 60)	Control group (n = 60)	OR	95% CI	P-value
Genotypic model	3A3A	18 (30.00)	31 (51.67)	Reference	-	-
	3A4A	37 (61.67)	26 (43.33)	2.451	1.138–5.280	0.022
	4A4A	5 (8.33)	3 (5.00)	2.870	0.612–13.453	0.182
Dominant model	3A3A	18 (30.00)	31 (51.67)	2.494	1.179–5.276	0.017
Dominant model	3A4A + 4A4A	42 (70.00)	29 (48.33)	2.494	1.179–5.276	0.017
Recessive model	3A3A + 3A4A	55 (91.67)	57 (95.00)	1.727	0.394–7.577	0.478
Recessive model	4A4A	5 (8.33)	3 (5.00)	1.727	0.394–7.577	0.478
Allelic model	3 A	73 (60.83)	88 (73.33)	1.771	1.026–3.056	0.040
Allelic model	4 A	47 (39.17)	32 (26.67)	1.771	1.026–3.056	0.040

Data are presented as number (%) unless otherwise specified
Ins/del A insertion/deletion of adenine, OR odds ratio, CI confidence interval