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Fig. 1 | Clinical Hypertension

Fig. 1

From: Clinical impact of guideline-based practice and patients’ adherence in uncontrolled hypertension

Fig. 1

Guideline-based practice and medication adherence. a)Guideline-based practice (GBP) was based on the JNC 8 guidelines and defined as systolic BP (SBP) ≥140 mmHg or diastolic BP (DBP) ≥90 mmHg and with the treatment strategies for antihypertensive drugs meeting one of the following: (1) maximize first medication before adding second, (2) add second medication before reaching the maximum dose of the first medication, or (3) start with two medication classes separately or as a fixed-dose combination. If BP was controlled (either SBP < 140 mmHg or DBP < 90 mmHg) at the next visit, GBP was determined as the same treatment strategies were implemented. b) Adherence was defined as patients showing high adherence according to Morisky Medication Adherence Scale-8 and moderate and low adherent patients were categorized as non-adherent [13,14,15]. c) Indicates that a comparison of 2 values showed a significant difference at P < 0.001. P-values for visit effect by generalized estimating equation method

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