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Fig. 2 | Clinical Hypertension

Fig. 2

From: Nonlinear analysis of heart rhythm in preeclampsia: a route for translational clinical applications in neuroinflammation

Fig. 2

Alterations in preeclampsia may involve increased cardiac sympathetic activity, decreased cardiac parasympathetic activity, and reduced complexity of heart rate fluctuations. These alterations may produce changes in nonlinear features of the maternal or fetal heart rate variability (mHRV and fHRV, respectively). A downregulated maternal cholinergic anti-inflammatory pathway (CAP) may result in a high pro-inflammatory state in the mother and fetus (increased levels of tumor necrosis factor-alpha [TNF-α], interleukin-6 [IL-6], and other pro-inflammatory cytokines). The assessment of nonlinear features of heart rate variability (HRV) is a potential tool for exploring the neuroinflammatory interactions in the maternal-fetal dyad

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Clinical Hypertension

ISSN: 2056-5909

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