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Table. 4 Effects of menopausal hormone therapy on arterial stiffness

From: Effects of menopausal hormone therapy on ambulatory blood pressure and arterial stiffness in postmenopausal Korean women with grade 1 hypertension: a randomized, placebo-controlled trial

 

Placebo (n = 16)

ET (n = 18)

EPT (n = 17)

Baseline 

12 weeks

Change from baseline

Baseline 

12 weeks

Change from baseline

Baseline 

12 weeks

Change from baseline

PWV

15.8 ± 2.2

16.3 ± 2.9

0.3 ± 1.5

15.2 ± 1.6

14.6 ± 1.7

-0.6 ± 1.6

15.4 ± 1.7

14.9 ± 1.3

-0.6 ± 1.4a

Ao SBP

137.3 ± 14.2

134.6 ± 13.7

-3.3 ± 13.8

135.9 ± 10.6

128.1 ± 18.3

-7.9 ± 15.3

140.9 ± 14.6

136.7 ± 16.2

-6.6 ± 17.0

Ao DBP

85.2 ± 10.5

86.3 ± 9.9

0.4 ± 7.5

87.7 ± 6.0

82.1 ± 10.3

-5.6 ± 9.1a

90.1 ± 9.0

87.9 ± 10.0

-3.6 ± 8.2

Ao PP

52.1 ± 7.7

48.3 ± 7.4

-3.7 ± 8.6

48.3 ± 9.7

46.0 ± 13.4

-2.3 ± 10.1

50.8 ± 11.3

48.8 ± 12.0

-2.9 ± 11.6

AIx

0.40 ± 0.09

0.39 ± 0.09

0.0 ± 0.1

0.39 ± 0.05

0.35 ± 0.07

0.0 ± 0.1a

0.40 ± 0.09

0.39 ± 0.09

0.0 ± 0.1

cAIx

0.35 ± 0.07

0.34 ± 0.06

0.0 ± 0.1

0.33 ± 0.05

0.34 ± 0.06

0.0 ± 0.1

0.35 ± 0.08

0.33 ± 0.07

0.0 ± 0.1

  1. Data are presented as means ± standard deviations
  2. ET estrogen therapy, EPT estrogen + progestogen therapy, Ao aortic, SBP systolic blood pressure (mmHg), DBP diastolic blood pressure (mmHg), PP pulse pressure (mmHg), PWV brachial–ankle pulse-wave velocity (m/s), AIx augmentation index, cAIx corrected augmentation index at heart rate 75 bpm
  3. aP-value for within-group difference between baseline and 12 weeks of treatment < 0.05, by the signed-rank test