Table. 3 Effect of menopausal hormone therapy on ambulatory blood pressure measures
|  | Placebo (n = 16) | ET (n = 18) | EPT (n = 17) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Baseline | 12 weeks | Change from baseline | Baseline | 12 weeks | Change from baseline | Baseline | 12 weeks | Change from baseline | |
Daytime measurement | |||||||||
SBP | 147.9 ± 14.3 | 146.9 ± 11.0 | -0.9 ± 12.5 | 148.0 ± 14.5 | 146.7 ± 20.0 | -1.3 ± 14.2 | 150.0 ± 11.6 | 148.5 ± 11.6 | -1.4 ± 9.5 |
DBP | 92.8 ± 9.4 | 91.0 ± 10.6 | -2.3 ± 8.7 | 93.5 ± 9.9 | 93.8 ± 11.4 | 0.3 ± 7.1 | 94.5 ± 10.4 | 93.3 ± 10.1 | -1.2 ± 6.1 |
HR | 72.8 ± 6.8 | 72.0 ± 7.4 | 0.1 ± 6.4 | 73.7 ± 6.3 | 72.2 ± 7.0 | -1.5 ± 6.3 | 76.6 ± 7.8 | 74.1 ± 7.4 | -2.5 ± 5.7 c |
BP loada | |||||||||
SBP | 77.0 ± 26.0 | 74.1 ± 25.5 | -2.4 ± 28.2 | 73.6 ± 26.8 | 65.8 ± 31.2 | -7.8 ± 29.0 | 77.4 ± 22.8 | 75.2 ± 20.5 | -2.2 ± 16.8 |
DBP | 74.3 ± 25.5 | 66.2 ± 30.9 | -10.5 ± 23.7 | 66.3 ± 23.6 | 66.6 ± 27.9 | 0.2 ± 24.6 | 71.2 ± 27.2 | 69.8 ± 31.0 | -1.4 ± 10.5 |
Nighttime measurement | |||||||||
SBP | 139.9 ± 16.8 | 136.4 ± 12.6 | -3.7 ± 12.4 | 135.1 ± 13.6 | 135.9 ± 17.3 | 0.8 ± 15.9 | 145.2 ± 12.1 | 143.9 ± 12.6 | -1.3 ± 10.7 |
DBP | 85.3 ± 11.5 | 82.4 ± 9.4 | -3.2 ± 7.8 | 83.5 ± 11.3 | 82.1 ± 9.8 | -1.4 ± 8.8 | 89.1 ± 10.0 | 87.7 ± 10.0 | -1.4 ± 4.3 |
HR | 64.0 ± 6.4 | 62.2 ± 6.6 | -1.2 ± 7.8 | 61.4 ± 6.3 | 61.6 ± 4.9 | 0.2 ± 3.4 | 66.2 ± 6.6 | 62.7 ± 5.9 | -3.5 ± 7.1 |
BP loada | |||||||||
SBP | 79.1 ± 25.9 | 77.8 ± 28.5 | -2.2 ± 32.1 | 70.7 ± 28.3 | 67.2 ± 31.8 | -3.5 ± 40.4 | 89.4 ± 17.8 | 82.3 ± 26.1 | -7.1 ± 21.1 |
DBP | 59.9 ± 27.9 | 49.4 ± 32.6 | -10.8 ± 28.3 | 56.3 ± 35.3 | 51.8 ± 34.6 | -4.5 ± 39.3 | 67.3 ± 33.4 | 61.4 ± 37.9 | -5.9 ± 24.3 |
Night dipb | |||||||||
SBP | -5.3 ± 7.4 | -7.8 ± 7.0 | -2.7 ± 6.3 | -8.3 ± 8.9 | -7.1 ± 4.1 | 1.2 ± 8.2 | -2.9 ± 7.9 | -3.0 ± 6.9 | -0.1 ± 5.2 |
DBP | -8.0 ± 7.9 | -9.6 ± 8.0 | -1.4 ± 7.5 | -10.3 ± 10.8 | -12.0 ± 8.7 | -1.7 ± 10.2 | -5.4 ± 7.6 | -5.8 ± 7.6 | -0.4 ± 5.0 |
24-hour measurement | |||||||||
SBP | 146.0 ± 14.1 | 144.4 ± 10.5 | -1.5 ± 11.7 | 144.8 ± 13.0 | 143.8 ± 19.2 | -1.0 ± 13.4 | 148.8 ± 10.6 | 147.3 ± 10.9 | -1.5 ± 9.3 |
DBP | 91.0 ± 9.4 | 89.0 ± 9.9 | -2.5 ± 7.9 | 91.2 ± 9.3 | 90.8 ± 10.4 | -0.3 ± 6.1 | 93.2 ± 9.7 | 91.9 ± 9.5 | -1.3 ± 5.4 |