Skip to main content

Table 2 List of 24 SNPs included to calculate genetic risk score for LDL-C

From: Inference of a causal relation between low-density lipoprotein cholesterol and hypertension using mendelian randomization analysis

Chromosome SNP Gene Risk allele Other allele β SE(β) F-statistic
1 rs41279716 CELSR2 A T 0.0518 0.0065 20.27
1 rs4970834 CELSR2 C T 0.1503 0.0047 33.26
1 rs79868705 CELSR2 G A 0.0851 0.0126 10.47
1 rs79482788 CELSR2 G A 0.0864 0.0126 10.49
1 rs12740374 CELSR2 G T 0.1610 0.0044 44.21
1 rs35358959 PSRC1 G A 0.0986 0.0088 18.94
1 rs672569 PSRC1 G A 0.1431 0.0082 19.47
1 rs11596737 PDLIM1 G A 0.0968 0.0088 20.86
1 rs17645031 MYBPHL C T 0.1004 0.0067 17.49
1 rs41306199 MYBPHL C T 0.0903 0.0091 17.49
11 rs651821 APOA5 C T 0.0722 0.0094 10.94
11 rs7952602 ST3GAL4 C G 0.0496 0.0054 10.67
16 rs8062041 TXNL4B T C 0.0250 0.0038 17.01
19 rs2738452 LDLR G A 0.0624 0.0053 19.06
19 rs2738464 LDLR C G 0.0422 0.0061 73.71
19 rs892114 SPC24 A G 0.0353 0.0047 14.01
19 rs6511727 DOCK6 T G 0.0266 0.0038 11.56
19 rs387976 NECTIN2 A C 0.0818 0.0057 33.17
19 rs3852861 NECTIN2 G T 0.0347 0.0041 17.18
19 rs7254892 NECTIN2 G A 0.4853 0.0119 241.13
19 rs7412 APOE C T 0.5898 0.0101 307.79
19 rs445925 APOC1 G A 0.3634 0.0081 206.40
19 rs56131196 APOC1 A G 0.2011 0.0076 27.28
19 rs7259004 APOC1P1 G C 0.2094 0.0092 30.97
  1. LDL-C Low-density lipoprotein cholesterol, SNP Single-nucleotide polymorphism, SE Standard error