Inference of a causal relation between low-density lipoprotein cholesterol and hypertension using mendelian randomization analysis

Table 2 List of 24 SNPs included to calculate genetic risk score for LDL-C

Chromosome	SNP	Gene	Risk allele	Other allele	β	SE(β)	F-statistic
1	rs41279716	CELSR2	A	T	0.0518	0.0065	20.27
1	rs4970834	CELSR2	C	T	0.1503	0.0047	33.26
1	rs79868705	CELSR2	G	A	0.0851	0.0126	10.47
1	rs79482788	CELSR2	G	A	0.0864	0.0126	10.49
1	rs12740374	CELSR2	G	T	0.1610	0.0044	44.21
1	rs35358959	PSRC1	G	A	0.0986	0.0088	18.94
1	rs672569	PSRC1	G	A	0.1431	0.0082	19.47
1	rs11596737	PDLIM1	G	A	0.0968	0.0088	20.86
1	rs17645031	MYBPHL	C	T	0.1004	0.0067	17.49
1	rs41306199	MYBPHL	C	T	0.0903	0.0091	17.49
11	rs651821	APOA5	C	T	0.0722	0.0094	10.94
11	rs7952602	ST3GAL4	C	G	0.0496	0.0054	10.67
16	rs8062041	TXNL4B	T	C	0.0250	0.0038	17.01
19	rs2738452	LDLR	G	A	0.0624	0.0053	19.06
19	rs2738464	LDLR	C	G	0.0422	0.0061	73.71
19	rs892114	SPC24	A	G	0.0353	0.0047	14.01
19	rs6511727	DOCK6	T	G	0.0266	0.0038	11.56
19	rs387976	NECTIN2	A	C	0.0818	0.0057	33.17
19	rs3852861	NECTIN2	G	T	0.0347	0.0041	17.18
19	rs7254892	NECTIN2	G	A	0.4853	0.0119	241.13
19	rs7412	APOE	C	T	0.5898	0.0101	307.79
19	rs445925	APOC1	G	A	0.3634	0.0081	206.40
19	rs56131196	APOC1	A	G	0.2011	0.0076	27.28
19	rs7259004	APOC1P1	G	C	0.2094	0.0092	30.97

LDL-C Low-density lipoprotein cholesterol, SNP Single-nucleotide polymorphism, SE Standard error

ISSN: 2056-5909