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Table 1 Baseline characteristics according to hypertension

From: Inference of a causal relation between low-density lipoprotein cholesterol and hypertension using mendelian randomization analysis

Variables

Normal

(N = 11,378)

Hypertension

(N = 8158)

p-value

Sex

  

<.0001

 Men

4077 (35.8)

3176 (38.9)

 

 Women

7301 (61.2)

4982 (61.1)

 

Age

57.2 ± 9.7

60.9 ± 9.0

<.0001

Family history of hypertension

1937 (17.2)

2104 (26.1)

<.0001

Smoking status

  

<.0001

 Never smoker

6367 (71.0)

4667 (70.9)

 

 Ex-smoker

1219 (13.6)

1059 (16.1)

 

 Current smoker

1386 (15.4)

853 (13.0)

 

Alcohol drinking

  

0.0002

 Never drinking

6069 (53.5)

4113 (50.5)

 

 Ex-drinking

782 (6.9)

628 (7.7)

 

 Current drinking

4500 (39.6)

3400 (41.8)

 

Exercise

  

<.0001

  < 3 times per weeks

878 (23.3)

514 (18.8)

 

  ≥ 3 times per weeks

2888 (76.7)

2214 (81.2)

 

Systolic blood pressure (mmHg)

116.2 ± 11.7

138.3 ± 17.0

<.0001

Diastolic blood pressure (mmHg)

73.9 ± 8.0

85.8 ± 11.0

<.0001

Body mass index (kg/m2)

23.9 ± 3.0

25.1 ± 3.2

<.0001

Waist circumference (cm)

82.5 ± 8.6

85.9 ± 8.7

<.0001

HDL-C (mg/dL)

45.7 ± 11.1

45.0 ± 11.1

<.0001

LDL-C (mg/dL)

124.5 ± 31.5

125.8 ± 33.7

0.0072

Total cholesterol (mg/dL)

195.8 ± 35.1

200.6 ± 36.8

<.0001

Triglyceride (mg/dL)

128.0 ± 64.9

148.9 ± 72.4

<.0001

Salt intake (mg)

2530.4 ± 1544.6

2470.1 ± 1517.2

<.0001

  1. Values are presented as a number (percentage) or mean ± standard deviation
  2. SBP Systolic blood pressure, DBP Diastolic blood pressure, BMI Body mass index, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol