Diagnostic criteria for pre-eclampsia [28] | |
---|---|
The onset of symptoms after 20 weeks’ gestation with remission by 6–12 weeks postpartum* | |
Mild pre-eclampsia: | |
 • Hypertension (Systolic Blood Pressure(SBP) ≥ 140 mmHg or Diastolic Blood Pressure(DBP) ≥ 90 mmHg), may be superimposed on chronic hypertension | |
 • Proteinuria (proteinuria ≥300 mg/24 h, or significant increase from baseline) | |
Severe pre-eclampsia if one or more of the following: | |
 • Sustained Systolic Blood Pressure(SBP) ≥ 160 mmHg or Diastolic Blood Pressure(DPB) ≥ 110 mmHg (measured twice, at least 6 h apart) | |
 • Evidence of other end-organ damage | |
  • Deteriorating renal function including nephrotic range proteinuria ≥3 g/24 h or 3+ on urine dipstick or sudden oliguria, especially with elevated creatinine†| |
  • Central Nervous System(CNS) disturbance (altered vision, headache) | |
  • Pulmonary edema (3% of patients) | |
  • Liver dysfunction | |
  • Epigastric/right upper quadrant pain (stretching of hepatic capsule) | |
  • Thrombocytopenia (15–30% of patients) | |
  • HELLP syndrome is characterized by Hemolysis Elevated Liver enzymes and Low platelet count which may occur without proteinuria. | |
  • Evidence of fetal compromise (Intrauterine Growth Restriction-IUGR, oligohydramnios, non-reasoning fetal testing) |