Table 3 Frequencies, odds ratios, and p-values of rs3752462genevariants among cases and controls under recessive, dominant, co-dominant, additive and allele models
Model | Allele | Controls (n = 132) | Cases (n = 132) | cOR (95% CI) | aOR (95% CI) |
|---|---|---|---|---|---|
Dominant model | wt/mt CT + mt/mt TT | 97.7% | 97.7% | 1 | 1 |
wt/wt CC | 2.3% | 2.3% | 1.00 (0.20–5.05) | 1.10 (0.19–6.29) | |
Recessive | wt/mt CT + wt/wt CC | 34.1% | 82.6% | 1 | 1 |
mt/mt TT | 65.9% | 17.4% | 0.11 (0.06–0.19)** | 0.12 (0.06–0.25)** | |
Co-dominant model | wt/mt CT + mt/mt TT | 68.2% | 19.7% | 1 | 1 |
wt/mt CT | 31.8% | 80.3% | 8.73 (4.97–15.36)** | 7.82 (3.81–16.04)** | |
Additive model 1 | wt/mt CT | 93.3% | 97.2% | 1 | 1 |
wt/wt CC | 6.7% | 2.8% | 0.40 (0.08–2.04) | 0.41 (0.07–2.44) | |
Additive model 2 | mt/mt TT | 96.7% | 88.5% | 1 | 1 |
wt/wt CC | 3.3% | 11.5% | 3.78 (0.71–20.0) | 4.0 (0.64–24.89) | |
Allele Model | T-allele | 97.7% | 97.7% | 1 | 1 |
C-allele | 34.1% | 82.6% | 9.16 (5.15–16.30)** | 8.29 (4.0–17.27)** |