Fig. 1

Restricted Cubic Splines Model for All-Cause Mortality According to On-Treatment BP. a SBP: all population. b SBP: heart failure with reduced ejection fraction (EF). c SBP: heart failure with preserved EF. d DBP: all population. e DBP: heart failure with reduced EF (EF). f DBP: heart failure with preserved EF. SBP, systolic blood pressure; DBP, diastolic blood pressure. Reprinted from JACC: Heart Failure, Vol 5, Lee SE, et al., Reverse J-Curve Relationship Between On-Treatment Blood Pressure and Mortality in Patients With Heart Failure, 810–819 No.11, 2017, with permission from Elsevier [36]