Familial aggregation and heritability of hypertension in Han population in Shanghai China: a case-control study

Clinical Hypertension

Table 2 The hypertension prevalence rate (%) of relatives in case and control group

	Control group			Case group			x²	p
	total	disease	prevalence	total	disease	prevalence	x²	p
First-degree relatives
Parent	570	203	35.61	583	314	53.86	14.853	0.000
Siblings	704	217	30.82	670	332	49.55	21.557	0.000
Offspring	440	33	7.50	419	67	15.99	11.899	0.001
	1714	453	26.43	1672	713	42.64	48.167	0.000
Second- degree relatives
Paternal siblings	791	123	15.55	802	168	20.95	5.375	0.020
Maternal siblings	740	107	14.46	770	148	19.22	4.339	0.037
	1531	230	15.02	1572	316	20.10	9.635	0.002
Third-degree relatives
Paternal cousin	176	14	7.95	175	32	18.29	6.330	0.012
Maternal cousin	825	97	11.76	934	142	15.20	3.897	0.046
	1001	111	11.09	1109	174	15.69	7.282	0.007
Total	4246	794	18.70	4353	1203	27.64	83.649	0.000

ISSN: 2056-5909