Compound | HDAC1 | HDAC2 | HDAC3 | HDAC8 |
---|
PCI34051 | 1.22 | > 10 | > 10 | 0.02 |
- The in vitro inhibitory activity of PCI34051 against each HDAC isoform was determined using the HDAC Fluorogenic Assay Kit from BPS Bioscience. The IC50 values were determined using 0.0001, 0.0003, 0.01, 0.03, 0.1, 0.3, 1, and 3 μM of the inhibitor.