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Fig. 5 | Clinical Hypertension

Fig. 5

From: Selective inhibition of histone deacetylase 8 improves vascular hypertrophy, relaxation, and inflammation in angiotensin II hypertensive mice

Fig. 5

PCI34051 inhibits the expression of adhesion molecules in aortic tissues of Ang II-infused mice VCAM-1 (a) and ICAM-1 (b) aortic mRNA expression levels were normalized to GAPDH and relative amounts were calculated. Data are presented as mean ± SEM (n = 8 per group). ** P < 0.01 versus sham-treated group; # P < 0.05 versus Ang II-infused group. c VCAM-1 expression was assessed by immunohistochemistry. Arrows indicate the expression of VCAM-1 in the aorta (brown). Scale bar = 50 μm. The lower Ang II-infused group image shows a negative control.

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