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Table 5 Relationship between ADRs and specific antihypertensive medications

From: Adverse effects and non-adherence to antihypertensive medications in University of Gondar Comprehensive Specialized Hospital

ADRs Medications COR p-value
Nausea Furosemide 5.509 (1.173–25.860) 0.031
Constipation Furosemide 4.750 (1.017–22.186) 0.048
Palpitation Amlodipine 2.136 (1.200–3.802) 0.010
Furosemide 5.357 (1.017–28.231) 0.048
Swollen feet or legs Amlodipine 2.263 (1.228–4.169) 0.009
Nifedipine 2.224 (1.145–4.317) 0.018
Atenolol 12.828 (1.406–17.055) 0.024
Cold hands or feet Furosemide 6.231 (1.321–29.393) 0.021
Atenolol 12.577 (2.008–78.782) 0.007
Cramps Nifedipine 3.421 (1.352–8.653) 0.009
Amlodipine 3.329 (1.435–7.723) 0.005
Enalapril 2.533 (1.271–5.044) 0.008
Persistent dry cough Amlodipine 0.448 (0.206–0.974) 0.043
Enalapril 6.348 (3.140–12.831) < 0.001
Skin rash Furosemide 7.667 (1.346–43.658) 0.022
Frequent urination Hydrochlorothiazide 6.866 (3.629–12.988) < 0.001
Nifedipine 0.428 (0.207–0.886) 0.022
Decreased sexual desire Hydrochlorothiazide 4.325 (1.831–10.216) 0.001
Enalapril 0.458 (0.221–0.950) 0.036