Table 5 Relationship between ADRs and specific antihypertensive medications
ADRs | Medications | COR | p-value |
|---|---|---|---|
Nausea | Furosemide | 5.509 (1.173–25.860) | 0.031 |
Constipation | Furosemide | 4.750 (1.017–22.186) | 0.048 |
Palpitation | Amlodipine | 2.136 (1.200–3.802) | 0.010 |
Furosemide | 5.357 (1.017–28.231) | 0.048 | |
Swollen feet or legs | Amlodipine | 2.263 (1.228–4.169) | 0.009 |
Nifedipine | 2.224 (1.145–4.317) | 0.018 | |
Atenolol | 12.828 (1.406–17.055) | 0.024 | |
Cold hands or feet | Furosemide | 6.231 (1.321–29.393) | 0.021 |
Atenolol | 12.577 (2.008–78.782) | 0.007 | |
Cramps | Nifedipine | 3.421 (1.352–8.653) | 0.009 |
Amlodipine | 3.329 (1.435–7.723) | 0.005 | |
Enalapril | 2.533 (1.271–5.044) | 0.008 | |
Persistent dry cough | Amlodipine | 0.448 (0.206–0.974) | 0.043 |
Enalapril | 6.348 (3.140–12.831) | < 0.001 | |
Skin rash | Furosemide | 7.667 (1.346–43.658) | 0.022 |
Frequent urination | Hydrochlorothiazide | 6.866 (3.629–12.988) | < 0.001 |
Nifedipine | 0.428 (0.207–0.886) | 0.022 | |
Decreased sexual desire | Hydrochlorothiazide | 4.325 (1.831–10.216) | 0.001 |
Enalapril | 0.458 (0.221–0.950) | 0.036 |