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Table 4 Predictors of poor adherence to antihypertensive medications among hypertensive patients attending UOGCSH (N = 249)

From: Adverse effects and non-adherence to antihypertensive medications in University of Gondar Comprehensive Specialized Hospital

Variables

Crude odds ratio (COR) (95% CI)

p-value

AOR (95% CI)

p-value

Age

 Years

1.025 (1.000–1.050)

0.048

0.994 (0.959–1.030)

0.738

Duration of antihypertensive medication use

 Years

1.122 (1.056–1.193)

0.000

1.080 (0.996–1.170)

0.062

Number of antihypertensive medications used

1.478 (0.976–2.239)

0.065

1.496 (0.804–2.784)

0.204

Hydrochlorothiazide

0.659 (0.392–1.109)

0.116

0.837 (0.404–1.732)

0.632

Nifedipine

2.865 (1.502–5.465)

0.001

2.389 (0.900–6.340)

0.080

Other medications

 Yes

1.870 (1.090–3.207)

0.023

2.633 (0.598–11.587)

0.200

Number of other medications

1.262 (0.949–1.678)

0.109

0.876 (0.401–1.917)

0.741

Tiredness

 Yes

3.122 (1.825–5.348)

0.000

3.802 (1.723–8.391)

0.001

Sweats

 Yes

2.055 (1.023–4.128)

0.043

0.790 (0.266–2.342)

0.670

Nausea

 Yes

1.779 (0.843–3.756)

0.131

0.654 (0.190–2.260)

0.503

Palpitation

 Yes

1.995 (1.159–3.432)

0.013

2.014 (0.790–5.137)

0.143

Cold hands and feet

 Yes

3.098 (1.391–6.899)

0.006

1.676 (0.463–6.064)

0.431

Muscle pain

 Yes

2.971 (1.286–6.864)

0.011

5.199 (1.407–19.214)

0.013

Cramps

 Yes

1.918 (0.781–4.711)

0.155

3.073 (0.632–14.933)

0.164

Headache

 Yes

1.444 (0.860–2.424)

0.164

1.062 (0.454–2.488)

0.889

Anxiety

 Yes

1.909 (0.876–4.162)

0.104

0.906 (0.247–3.331)

0.882

Sleep poorly

 Yes

2.061 (1.054–4.029)

0.035

4.891 (1.578–15.160)

0.006

Skin rash

 Yes

3.171 (1.029–9.774)

0.044

2.132 (0.373–12.193)

0.395

Decreased sexual desire

 Yes

0.494 (0.229–1.065)

0.072

0.643 (0.203–2.043)

0.454

Number of adverse effects

1.140 (1.039–1.250)

0.005

0.776 (0.592–1.017)

0.066

Symptoms are caused by medications

 I don’t know

1

 

1

 

 Yes

1.348 (0.669–2.714)

0.403

3.249 (1.248–8.456)

0.016

 No

2.141 (1.131–4.049)

0.019

1.720 (0.673–4.392)

0.257

Symptoms caused to change or stop medications

10.554 (4.169–26.717)

0.000

16.104 (4.164–62.290)

0.000

Regular exercise

 Yes

0.363 (0.209–0.632)

0.000

0.170 (0.072–0.402)

0.000