|
Age
|
|
Years
|
1.025 (1.000–1.050)
|
0.048
|
0.994 (0.959–1.030)
|
0.738
|
|
Duration of antihypertensive medication use
|
|
Years
|
1.122 (1.056–1.193)
|
0.000
|
1.080 (0.996–1.170)
|
0.062
|
|
Number of antihypertensive medications used
|
1.478 (0.976–2.239)
|
0.065
|
1.496 (0.804–2.784)
|
0.204
|
|
Hydrochlorothiazide
|
0.659 (0.392–1.109)
|
0.116
|
0.837 (0.404–1.732)
|
0.632
|
|
Nifedipine
|
2.865 (1.502–5.465)
|
0.001
|
2.389 (0.900–6.340)
|
0.080
|
|
Other medications
|
|
Yes
|
1.870 (1.090–3.207)
|
0.023
|
2.633 (0.598–11.587)
|
0.200
|
|
Number of other medications
|
1.262 (0.949–1.678)
|
0.109
|
0.876 (0.401–1.917)
|
0.741
|
|
Tiredness
|
|
Yes
|
3.122 (1.825–5.348)
|
0.000
|
3.802 (1.723–8.391)
|
0.001
|
|
Sweats
|
|
Yes
|
2.055 (1.023–4.128)
|
0.043
|
0.790 (0.266–2.342)
|
0.670
|
|
Nausea
|
|
Yes
|
1.779 (0.843–3.756)
|
0.131
|
0.654 (0.190–2.260)
|
0.503
|
|
Palpitation
|
|
Yes
|
1.995 (1.159–3.432)
|
0.013
|
2.014 (0.790–5.137)
|
0.143
|
|
Cold hands and feet
|
|
Yes
|
3.098 (1.391–6.899)
|
0.006
|
1.676 (0.463–6.064)
|
0.431
|
|
Muscle pain
|
|
Yes
|
2.971 (1.286–6.864)
|
0.011
|
5.199 (1.407–19.214)
|
0.013
|
|
Cramps
|
|
Yes
|
1.918 (0.781–4.711)
|
0.155
|
3.073 (0.632–14.933)
|
0.164
|
|
Headache
|
|
Yes
|
1.444 (0.860–2.424)
|
0.164
|
1.062 (0.454–2.488)
|
0.889
|
|
Anxiety
|
|
Yes
|
1.909 (0.876–4.162)
|
0.104
|
0.906 (0.247–3.331)
|
0.882
|
|
Sleep poorly
|
|
Yes
|
2.061 (1.054–4.029)
|
0.035
|
4.891 (1.578–15.160)
|
0.006
|
|
Skin rash
|
|
Yes
|
3.171 (1.029–9.774)
|
0.044
|
2.132 (0.373–12.193)
|
0.395
|
|
Decreased sexual desire
|
|
Yes
|
0.494 (0.229–1.065)
|
0.072
|
0.643 (0.203–2.043)
|
0.454
|
|
Number of adverse effects
|
1.140 (1.039–1.250)
|
0.005
|
0.776 (0.592–1.017)
|
0.066
|
|
Symptoms are caused by medications
|
|
I don’t know
|
1
| |
1
| |
|
Yes
|
1.348 (0.669–2.714)
|
0.403
|
3.249 (1.248–8.456)
|
0.016
|
|
No
|
2.141 (1.131–4.049)
|
0.019
|
1.720 (0.673–4.392)
|
0.257
|
|
Symptoms caused to change or stop medications
|
10.554 (4.169–26.717)
|
0.000
|
16.104 (4.164–62.290)
|
0.000
|
|
Regular exercise
|
|
Yes
|
0.363 (0.209–0.632)
|
0.000
|
0.170 (0.072–0.402)
|
0.000
|
