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Table 1 Summary of case reports previously reported in the literature

From: Renin dependent hypertension caused by accessory renal arteries

  Patient 1 (reference [15]) Patient 2 (reference [15]) Patient 3 (reference [21])
Clinical Patient with severe hypertension (BP 190/130 mmHg) partially controlled with 2 antihypertensive medications. Young adolescent with uncontrolled hypertension (BP 220/115 mmHg) treated with beta blocker and diuretic. Uncontrolled hypertension in a young patient investigated for secondary hypertension.
Hormonal studies PA 15 ng/dL
PRA 8 ng/ml/hour
ARR 1.8
PA 23 ng/dL
PRA 18 ng/ml/hour
ARR 1.3
Supine renin 400 pg/mL (Normal 2.4–21.9)
Selective renal vein sampling Renin vein (right/left) ratio 4.3:1 after captopril Renin vein (right/left) ratio 8:1 after captopril  
Imaging Arteriogram showed elongated, nonstenotic aberrant artery arising from the common iliac artery supplying the lower pole of the right kidney Arteriogram showed nonstenotic aberrant artery arising from the lower aorta feeding the lower pole of the left kidney Digital subtraction angiography showed small (2-mm) left accessory RA entrapped by the diaphragmatic crus with 90% proximal ostial segment stenosis
Medication Propranolol 50 mg twice per day and hydrochlorothiazide 50 mg/d Metoprolol 50 mg twice per day and hydrochlorothiazide 50 mg a day Atenolol 50 mg & amlodipine 10 mg daily
Outcome BP 120/70 mmHg off antihypertensive after left partial nephrectomy. Medical therapy with captopril, diuretic and beta blocker. Subsequently lost to follow up. Decision was made for medical therapy
  1. PA plasma aldosterone expressed in ng/dl [conversion factor to SI (pmol/L = 27.741], PRA plasma renin activity