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Table 2 Fetal and placental measurements at GD 18.5

From: Apolipoprotein A1 mimetic peptide ATI-5261 reverses arterial stiffness at late pregnancy and early postpartum in a COMT−/− mouse model of preeclampsia

Parameters

COMT−/− mice

C57BL/6 J mice

Vehicle (n = 8)

ATI-5261 (n = 8)

Vehicle (n = 8)

Litter size, n

8.1 ± 0.5

8.7 ± 0.4

9.1 ± 0.6

Pup weight, mg

895.5 ± 22.8a

958.2 ± 19.8a

1225.6 ± 25.6b

Crown to rump length, mm

27.5 ± 0.7a

28.6 ± 0.5ab

30.4 ± 0.6b

Abdominal circumference, mm

26.1 ± 0.9a

27.7 ± 0.8ab

29.2 ± 0.8b

Placental weight, mg

98.5 ± 2.8a

88.9 ± 2.3b

85.9 ± 2.6b

Fetal to placental ratio

9.4 ± 0.4a

11.1 ± 0.4b

14.8 ± 0.5c

#Reabsorption rate, %

10.4

7.7

3.4

  1. Data are presented as mean ± SEM. Groups were compared using one-way ANOVA with post-hoc analysis (Tukey’s procedure). Groups which do not share the same letter are significantly different from each other
  2. #Number of reabsorbed embryos per total number of embryos in each group