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Table 4 Diagnostic performance of ICG-derived indexes for identification of LVDD, for the identified cut-off points (n = 157)

From: Systolic time ratio measured by impedance cardiography accurately screens left ventricular diastolic dysfunction in patients with arterial hypertension

Index and cut-off TP FP TN FN Sensitivity %
(95% CI)
Specificity %
(95% CI)
PPV %
(95% CI)
NPV %
(95% CI)
PEP
≤ 104 ms
92 24 31 10 90.2
(82.7–95.2)
56.4
(42.3–69.7)
79.3
(73.8–83.9)
75.6
(62.2–85.4)
LVET
≥ 290 ms
92 28 27 10 90.2
(82.7–95.2)
49.1
(35.4–62.9)
76.6
(71.6–81.1)
72.9
(58.6–83.8)
STR
≤ 0.31
101 5 50 1 99.0
(94.7–99.9)
90.9
(80.0–96.9)
95.3
(89.8–97.9)
98.0
(87.7–99.7)
D wave presence 81 2 53 21 79.4
(70.3–86.8)
96.4
(87.5–99.6)
97.6
(91.2–99.4)
71.6
(63.2–78.8)
  1. FN false negative diagnostics, FP false positive diagnostics, NPV negative predictive value, LVDD left ventricular diastolic dysfunction, LVET left ventricle ejection time, PEP pre-ejection period, PPV positive predictive value, STR systolic time ratio, TN true negative diagnostics, TP true positive diagnostics