Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population

Clinical Hypertension

Table 2 Genotype distribution and HWE tests for all nine diallelic polymorphisms in the AGT Gene

dbSNP ID	Minor Allele (A1)	A2	Group	Genotype Distribution		HWE
				GENO	p-value	O(HET)	E(HET)	p-value
rs5046	T	C	Hypertensive	14/90/152	0.655	0.3516	0.3547	0.861
rs5046	T	C	Normotensive	12/52/94	0.655	0.3291	0.3653	0.198
rs5049	A	G	Hypertensive	14/94/148	0.684	0.3672	0.363	1
rs5049	A	G	Normotensive	12/56/90	0.684	0.3544	0.3781	0.406
rs11568020	A	G	Hypertensive	0/20/236	0.004	0.07812	0.07507	1
rs11568020	A	G	Normotensive	0/2/156	0.004	0.01266	0.01258	1
rs5050	C	A	Hypertensive	34/74/148	0.000	0.2891	0.4008	0.000
rs5050	C	A	Normotensive	4/30/124	0.000	0.1899	0.2116	0.244
rs5051	G	A	Hypertensive	28/90/138	0.292	0.3516	0.4077	0.031
rs5051	G	A	Normotensive	12/66/80	0.292	0.4177	0.4074	0.846
rs2148582	T	C	Hypertensive	26/90/140	0.170	0.3516	0.4008	0.060
rs2148582	T	C	Normotensive	10/68/80	0.170	0.4304	0.4019	0.433
rs3789679	T	C	Hypertensive	0/50/206	*	0.1953	0.1762	0.145
rs3789679	T	C	Normotensive	2/24/132	*	0.1519	0.1615	0.342
rs4762	T	C	Hypertensive	8/70/178	0.000	0.2734	0.2795	0.659
rs4762	T	C	Normotensive	0/36/122	0.000	0.2278	0.2019	0.224
rs699	T	C	Hypertensive	28/88/140	0.023	0.3438	0.4043	0.019
rs699	T	C	Normotensive	8/72/78	0.023	0.4557	0.4019	0.114

Significance values are italicized, Level of significance <0.05; Chi-Sq = 4.384; Degrees of freedom (DF) = 2; 1 cells with expected counts less than 1.0;*Chi-Square approximation probably invalid; 2 cells with expected counts less than 5.0

ISSN: 2056-5909