Table 1 Baseline clinical and laboratory characteristics
Total = 2951 | Group 1 (n = 2152) | Group 2 (n = 200) | Group 3 (n = 319) | Group 4 (n = 280) | p value |
|---|---|---|---|---|---|
Demographic data | |||||
Age, year *‡∥ | 52 ± 10 | 56 ± 9 | 57 ± 9 | 56 ± 9 | <0.001 |
Gender, male, n (%) ¶ | 887 (41.2) | 98 (49.0) | 151 (47.3) | 199 (71.1) | 0.003 |
Hypertension, n (%) ¶ | 567 (26.3) | 57 (28.5) | 18 (5.6) | 142 (50.7) | 0.949 |
Diabetes mellitus, n (%) | 191 (8.9) | 30 (15.0) | 9 (2.8) | 27 (9.6) | 0.359 |
Dyslipidemia, n (%) | 284 (13.2) | 26 (13.0) | 15 (4.7) | 44 (15.7) | 0.569 |
Familial history of CVA, n (%) | 573 (26.6) | 61 (30.5) | 24 (7.5) | 93 (33.2) | 0.245 |
Body mass index, Kg/m2 ‡∥ | 24.6 ± 3.7 | 24.9 ± 3.4 | 25.8 ± 4.1 | 25.6 ± 4.0 | < 0.001 |
Systolic BP, mm Hg ‡∥ | 122 ± 14 | 127 ± 14 | 127 ± 17 | 126 ± 13 | < 0.001 |
Diastolic BP, mm Hg *‡∥ | 72 ± 10 | 75 ± 10 | 76 ± 11 | 75 ± 10 | < 0.001 |
Heart rate, beats per minute * | 64 ± 10 | 65 ± 11 | 65 ± 10 | 64 ± 11 | 0.054 |
Smoking status, n (%) | 94 (4.4) | 6 (3.0) | 13 (0.9) | 78 (27.9) | 0.003 |
Laboratory findings | |||||
Total cholesterol, mg/dL | 204 ± 36 | 198 ± 39 | 203 ± 40 | 204 ± 35 | 0.416 |
Triglyceride, mg/dL∥ | 116 ± 81 | 126 ± 99 | 120 ± 79 | 133 ± 79 | 0.045 |
HDL-C, mg/dL ‡∥ | 52 ± 13 | 51 ± 11 | 50 ± 12 | 49 ± 11 | 0.006 |
LDL-C, mg/dL * | 125 ± 32 | 129 ± 30 | 125 ± 36 | 124 ± 33 | 0.313 |
Fasting blood glucose, mg/dL *‡ | 94 ± 21 | 102 ± 34 | 101 ± 24 | 99 ± 21 | 0.008 |
HbA1c,% *‡ | 5.6 ± 0.7 | 6.0 ± 1.4 | 5.9 ± 0.8 | 5.7 ± 0.6 | < 0.001 |
C reactive protein, mg/dL | 0.16 ± 0.41 | 0.16 ± 0.27 | 0.19 ± 0.32 | 0.18 ± 0.30 | 0.521 |