Table 1 Guideline comparisons of goal BP and initial drug therapy for adults with hypertension

JNC 8: 2014 Hypertension Guideline [3]

General ≥60 y

<150/90

Nonblack: thiazide-type diuretic, ACEI, ARB, or CCB; black: thiazide-type diuretic or CCB

General <60 y

<140/90

Diabetes

<140/90

CKD

<140/90

ACEI or ARB

ESH/ESC 2013 [42]

General nonelderly

<140/90

Diuretic, BB, CCB, ACEI, or ARB

General elderly <80 y

<150/90

General ≥80 y

<150/90

Diabetes

<140/85

ACEI or ARB

CKD no proteinuria

<140/90

CKD + proteinuria

<130/90

Canadian Hypertension Education Program (CHEP) 2014 [43]

General <80 y

<140/90

Thiazide, BB (age <60y), ACEI (nonblack), or ARB

General ≥80 y

<150/90

Diabetes

<130/80

ACEI or ARB with additional CVD risk ACEI, ARB, thiazide, or dihydropyridine CCB without additional CVD risk

CKD

<140/90

ACEI or ARB

American Diabetes Association (ADA) 2013 [44]

Diabetes

<140/80

ACEI or ARB

Kidney Disease: Improving Global Outcome (KDIGO) 2012 [45]

CKD, no proteinuria

≤140/90

ACEI or ARB

CKD + proteinuria

≤130/80

NICE 2011 [46]

General <80 y

<140/90

<55 y: ACEI or ARB

General ≥80 y

<150/90

≥55 y or black: CCB

International Society for Hypertension in Blacks (ISHIB) 2010 [47]

Black, lower risk

<135/85

Diuretic or CCB

Target organ damage or CVD risk

<130/80

Korean Society of Hypertension Guidelines for the Management of Hypertension 2013 [48]

Elderly (>65 years)

<140/90

ACEIs, CCBs and diuretics; BBs should be limited to special scenarios

Diabetes

<140/85

Stroke, CAD and CKD

140/90

Combination therapy of ARBs, CCBs and diuretics