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Table 1 Guideline comparisons of goal BP and initial drug therapy for adults with hypertension

From: A review on prescribing patterns of antihypertensive drugs

Guideline Population Goal BP, mmHg Initial drug treatment options
JNC 8: 2014 Hypertension Guideline [3] General ≥60 y <150/90 Nonblack: thiazide-type diuretic, ACEI, ARB, or CCB; black: thiazide-type diuretic or CCB
General <60 y <140/90
Diabetes <140/90
CKD <140/90 ACEI or ARB
ESH/ESC 2013 [42] General nonelderly <140/90 Diuretic, BB, CCB, ACEI, or ARB
General elderly <80 y <150/90
General ≥80 y <150/90
Diabetes <140/85 ACEI or ARB
CKD no proteinuria <140/90
CKD + proteinuria <130/90
Canadian Hypertension Education Program (CHEP) 2014 [43] General <80 y <140/90 Thiazide, BB (age <60y), ACEI (nonblack), or ARB
General ≥80 y <150/90
Diabetes <130/80 ACEI or ARB with additional CVD risk ACEI, ARB, thiazide, or dihydropyridine CCB without additional CVD risk
CKD <140/90 ACEI or ARB
American Diabetes Association (ADA) 2013 [44] Diabetes <140/80 ACEI or ARB
Kidney Disease: Improving Global Outcome (KDIGO) 2012 [45] CKD, no proteinuria ≤140/90 ACEI or ARB
CKD + proteinuria ≤130/80
NICE 2011 [46] General <80 y <140/90 <55 y: ACEI or ARB
General ≥80 y <150/90 ≥55 y or black: CCB
International Society for Hypertension in Blacks (ISHIB) 2010 [47] Black, lower risk <135/85 Diuretic or CCB
Target organ damage or CVD risk <130/80
Korean Society of Hypertension Guidelines for the Management of Hypertension 2013 [48] Elderly (>65 years) <140/90 ACEIs, CCBs and diuretics; BBs should be limited to special scenarios
Diabetes <140/85
Stroke, CAD and CKD 140/90 Combination therapy of ARBs, CCBs and diuretics