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Table 5 Comparison of predictive values of different scores regarding all cause mortality and readmissions among CHF patients

From: The utility of biomarker risk prediction score in patients with chronic heart failure

Models

AUC ROC

P value

IDI, %

P value

NRI, %

P value

Prediction of risk of one year all-cause mortality

Seattle Heart Failure Model (Standard)

0,738 ± 0,16

0,001

-

-

-

-

Heart Failure Risk Calculator

0.779 ± 0.19

0.001

6.4 ± 0.7 %

0,001

10.1 ± 0.99 %

0.002

Barcelona Bio-HF without biomarker assay

0.788 ± 0.15

0.002

7.9 ± 0.6 %

0.001

12.8 ± 1.21 %

0.002

Barcelona Bio-HF with biomarker assay

0.798 ± 0.13

0.002

11.4 ± 0.7 %

0.003

15.7 ± 1.18 %

0.001

Biomarker risk predictive score*

0.803 ± 0.11

0.001

13.9 ± 0.9 %

0,001

19.6 ± 1.65 %

0.002

Prediction of risk of two year all-cause mortality

Seattle Heart Failure Model (Standard)

0.722 ± 0.15

0.002

-

-

-

-

Barcelona Bio-HF without biomarker assay

0.732 ± 0.16

0.003

5.3 ± 0.3 %

0.001

6.8 ± 0.92 %

0.003

Barcelona Bio-HF with biomarker assay

0.744 ± 0.14

0.001

6.8 ± 0.5 %

0.001

7.5 ± 1.10 %

0.003

Biomarker risk predictive score*

0.768 ± 0.11

0.001

10.1 ± 1.02 %

0.001

17.1 ± 1.54 %

0.001

Prediction of risk of three year all-cause mortality

Seattle Heart Failure Model (Standard)

0.743 ± 0.12

0.002

-

-

-

-

Heart Failure Risk Calculator

0.788 ± 0.14

0.001

7.2 ± 0.2 %

0,001

12.5 ± 1.09 %

0.001

Barcelona Bio-HF without biomarker assay

0.796 ± 0.12

0.003

7.9 ± 0.5 %

0.001

17.6 ± 1.23 %

0.002

Barcelona Bio-HF with biomarker assay

0.805 ± 0.09

0.001

11.4 ± 1.12 %

0.003

22.1 ± 1.55 %

0.001

Biomarker risk predictive score*

0.818 ± 0,14

0.001

13.9 ± 1.15 %

0.001

28.9 ± 2.3 %

0.002

Prediction of risk of one year readmission

National Heart Care Project (Standard)

0.762 ± 0.16

0.001

-

-

-

-

Biomarker risk predictive score*

0.844 ± 0.15

0.001

15.5 ± 1.60 %

0.002

31.7 ± 2.77 %

0.001

  1. Note: AUC area under curve, ROC receive operation characteristic curve, IDI integrated discrimination improvement, NRI net reclassification improvement, *original risk predictive score based on biomarker assay