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Table 1 Baseline patient characteristics

From: The platelet-to-lymphocyte ratio reflects the severity of obstructive sleep apnea syndrome and concurrent hypertension

  Control (n = 61) Mild OSAS (n = 67) Moderate OSAS (n = 61) Severe OSAS (n = 101) ANOVA p
Age, years 44.0 ± 15.4 48.2 ± 13.4 49.1 ± 11.8 51.4 ± 12.5* 0.003
Male, n (%) 33 (54.1) 39 (58.2) 41 (67.2)* 80 (79.2)* <0.001
BMI, kg/m2 24.2 ± 4.43 24.7 ± 3.20 26.4 ± 3.58*,+ 26.9 ± 3.41*,+ <0.001
SBP, mmHg 123.4 ± 13.7 123.5 ± 13.1 128.5 ± 13.6* 128.2 ± 12.4* 0.027
DBP, mmHg 78.4 ± 10.7 77.0 ± 8.9 80.8 ± 9.2 81.2 ± 9.9* 0.039
Heart rate, /min 72.6 ± 7.90 73.3 ± 10.3 76.3 ± 10.5 76.7 ± 9.15* 0.020
Hypertension, n (%) 5 (8.2) 13 (19.4) 18 (29.5)* 30 (29.7)* 0.005
Diabetes mellitus, n (%) 1 (1.6) 2 (3.0) 4 (6.6) 13 (12.9) * 0.048
Dyslipidemia, n (%) 2 (3.3) 2 (3.0) 3 (4.9) 3 (3.0) 0.917
Smoking, n (%) 6 (9.8) 14 (20.9) 12 (19.7) 18 (17.8) 0.123
Total cholesterol, mg/dl 170.0 ± 38.2 184.0 ± 34.6 190.6 ± 45.6 172.4 ± 46.9 0.161
TG, mg/dl 141.1 ± 84.8 151.2 ± 8.03 160.8 ± 89.1 176.1 ± 144.9 0.606
FBS, mg/dl 101.5 ± 17.2 92.8 ± 10.3 105.8 ± 21.7 111.6 ± 45.3 0.034
ESR, mm/hr 7.8 ± 11.6 17.9 ± 30.2 15.5 ± 15.3 14.0 ± 10.9 0.224
hs-CRP, mg/L 0.53 ± 1.32 1.14 ± 2.28 0.82 ± 1.38 1.12 ± 2.08 0.529
WBC, x106/L 6759 ± 1806 7283 ± 2031 7314 ± 2976 7724 ± 2051 0.103
Neutrophil, % 53.1 ± 11.2 59.1 ± 11.0 55.1 ± 13.8 60.5 ± 10.3* 0.001
Lymphocyte, % 36.1 ± 9.87 33.0 ± 12.8 30.0 ± 9.22 27.4 ± 8.35* <0.001
Eosinophil, % 2.24 ± 1.66 3.01 ± 2.03 2.60 ± 1.99 2.90 ± 2.16 0.217
Monocyte, % 7.91 ± 2.54 7.44 ± 2.15 8.51 ± 5.96 7.35 ± 1.71 0.234
RBC, x109/L 4587 ± 423.9 4692 ± 377.2 4660 ± 282.4 4599 ± 378.1 0.286
Hemoglobin, g/dl 13.5 ± 1.5 14.0 ± 1.4 13.8 ± 1.6 14.4 ± 1.6* 0.004
Hematocrit, % 40.2 ± 4.4 41.2 ± 4.2 40.2 ± 6.6 42.5 ± 4.5* 0.010
RDW, % 13.5 ± 1.57 13.3 ± 1.25 13.5 ± 1.05 13.3 ± 0.76 0.735
Platelet, x109/L 216.7 ± 54.4 224.8 ± 56.0 231.3 ± 80.6 252.4 ± 66.8* 0.007
PLR 99.5 ± 42.1 113.8 ± 45.2 121.3 ± 62.9* 138.6 ± 59.9* 0.001
PDW, % 15.9 ± 1.12 16.3 ± 0.95 16.4 ± 0.99* 16.5 ± 0.82* 0.003
  1. All values are presented as means ± SD. BP, blood pressure; hs-CRP, high sensitivity C-reactive protein; OSAS: obstructive sleep apnea syndrome; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglyceride; FBS, fasting blood sugar; ESR, erythrocyte sedimentation rate; WBC, white blood cell; RBC, white blood cell; RDW, red cell distribution width; PLR, platelet lymphocyte ratio; PDW, platelet volume distribution width, *p < 0.05 vs. control group, + p < 0.05 vs. mild OSAS group