Figure 9
From: Depressor action and vasorelaxation of methylene chloride fraction extracted from Rubus coreanum
(A) Influence of intravenous methylene chloride (CH 2 Cl 2 ) fraction on norepinephrine (NE)-evoked pressor responses and (B) the representative tracing of effect of CH 2 Cl 2 fraction on intravenous NE-induced pressor responses in anesthetized rats. CH2Cl2 fraction (3.0 mg/kg/30 min) was given intravenously after obtaining the corresponding control responses of intravenous NE (0.3, 1.0, and 3.0 μg/kg, respectively). **p < 0.01. At arrow marks, the indicated doses (0.3, 1.0, and 3.0 μg/kg) of NE were administered into a femoral vein. (A) NE-induced hypertensive responses in a non-treated rat. (B) NE-induced hypertensive responses in a CH2Cl2 fraction-pretreated rat. CH2Cl2 fraction was infused into a femoral vein with a rate of 3 mg/kg/30 min. Arterial blood pressure from preinjection level was expressed in -mmHg. The chart speed was 10 mm/min. i.v., intravenously.