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Table 3 Summary of the longitudinal studies with altered short-term BPV and association with CKD progression

From: Short-term blood pressure variability as a potential therapeutic target for kidney disease

Study

Study subject

No. of subjects

Indices of BPV

Type of association

Outcome

Agarwal et al. [66]

With/without CKD

217

Nondipping

Indifferent

ESKD

Agarwal et al. [65]

CKD

322

Nondipping

Indifferent

ESKD

Borrelli et al. [71]

CKD

906

Nondipping

Positive

Initiation of dialysis or eGFR decline ≥ 50%

Davidson et al. [72]

CKD

322

Nondipping

Positive

Rapid decline in eGFR

Ida et al. [68]

CKD

1,107

Nondipping

Indifferent

Initiation of RRT or eGFR decline ≥ 40%

Liu et al. [75]

CKD

304

MBPS

Positive

ESKD or eGFR decline ≥ 50%

Borrelli et al.[20]

CKD

465

wSD and CV

Indifferent

ESKD or eGFR decline ≥ 50%

Jhee et al. [73]

CKD

470

ARV

Positive

Rapid kidney function declinea)

Rahman et al. [70]

CKD

1,502

Nondipping or reverse dipping

Positive

ESKD or eGFR decline ≥ 50%

Redon et al. [67]

CKD

79

Nondipping

Indifferent

Rapid decline in eGFRa)

Wang et al. [69]

CKD

588

Reverse dipping

Positive

ESKD or doubling of serum creatinine

Wang et al. [74]

CKD

1,421

wSD

Positive

ESKD

  1. BPV Blood pressure variability, CKD Chronic kidney disease, ESKD End-stage kidney disease, eGFR estimated glomerular filtration rate, RRT Renal replacement therapy, MBPS Morning blood pressure surge, ARV Average real variability, wSD weighted standard deviation, CV Coefficient of variation
  2. a)eGFR decline > 3 mL/min/1.73 m2 per year