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Table 3 Hazard ratios for mortality according to d-dimer tertile

From: Association between D-dimer and long-term mortality in patients with acute severe hypertension visiting the emergency department

 

Unadjusted HR

(95% CI)

Model 1a

(95% CI)

Model 2b

(95% CI)

Model 3c

(95% CI)

All patients

 Tertile 1*

REF

REF

REF

REF

 Tertile 2

5.725 (4.135–7.925)

3.223 (2.310–4.498)

3.094 (2.216–4.321)

2.847 (2.037–3.978)

 Tertile 3

18.290 (13.419–24.930)

8.506 (6.152–11.762)

7.595 (5.472–10.542)

6.440 (4.628–8.961)

Patients with acute HMOD

 Tertile 1*

REF

REF

REF

REF

 Tertile 2

5.486 (3.459–8.700)

3.177 (1.984–5.090)

3.036 (1.893–4.869)

2.939 (1.831–4.717)

 Tertile 3

17.112 (11.018–26.575)

8.130 (5.144–12.849)

7.506 (4.727–11.918)

6.802 (4.266–10.846)

Patients without acute HMOD

 Tertile 1*

REF

REF

REF

REF

 Tertile 2

5.641 (3.563–8.932)

3.180 (1.981–5.105)

3.037 (1.892–4.875)

2.694 (1.675–4.334)

 Tertile 3

17.629 (11.382–27.305)

8.381 (5.282–13.297)

7.358 (4.618–11.724)

6.215 (3.881–9.952)

  1. CI Confidence interval, HR Hazard ratio, REF Reference
  2. *The range of d-dimer levels in tertile 1 was < 116 ng/mL
  3. The range of d-dimer levels in tertile 2 is 116–356 ng/mL
  4. The range of d-dimer level in tertile 3 was > 356 ng/mL
  5. aModel 1 was adjusted for age, sex, and systolic and diastolic blood pressure
  6. bModel 2 was adjusted for age, sex, systolic blood pressure, diastolic blood pressure, and comorbidities (hypertension, diabetes mellitus, dyslipidemia, ischemic stroke, hemorrhagic stroke, coronary artery disease, heart failure, and chronic kidney disease)
  7. cModel 3 was adjusted for age, sex, systolic blood pressure, diastolic blood pressure, comorbidities (hypertension, diabetes mellitus, dyslipidemia, ischemic stroke, hemorrhagic stroke, coronary artery disease, heart failure, and chronic kidney disease), and components of hypertension-mediated organ damage (estimated glomerular filtration rate, hemoglobin level, cardiomegaly on chest radiography, left ventricular hypertrophy on electrocardiography, myocardial ischemia on electrocardiography, and atrial fibrillation on electrocardiography)