Skip to main content

Table 3 Univariate and multivariate Cox regression analysis adjusted heart failure medication

From: The utility of biomarker risk prediction score in patients with chronic heart failure

Variances

Univariate analysis

Multivariate analysis

OR

95 % CI

Р value

OR

95 % CI

Р value

Creatinine per 30 μmol/L

1.06

1.01–1.11

0.001

1.02

0.87–1.06

0.44

Fasting glucose per 3 mmol/L

1.04

0.96–1.09

0.22

Not included

HbA1c per 1 %

1.05

1.00–1.07

0.12

Not included

Total cholesterol per 1 mmol/L

1.08

1.00–1.09

0.12

Not included

Uric acid per 10 mmol/L

1.08

1.03–1.09

0.001

1.03

0.92–1.08

0.52

NT-pro-BNP per 400 pg/mL

1.97

1.25–3.06

0.001

1.37

1.08–2.10

0.001

Galectin-3 per 2.5 ng/mL

2.16

1.78–3.77

0.001

1.46

1.22–1.89

0.003

hs-CRP per 1 mg/L

1.42

1.22–1.87

0.001

1.12

1.03–1.25

0.001

Osteoprotegerin per 325 pg/mL

1.34

1.18–1.62

0.006

1.19

1.12–1.33

0.001

Osteopontin per 65 ng/mL

1.16

1.03–1.36

0.002

0.95

0.87–1.11

0.86

Osteonectin per 50 ng/mL

1.19

1.07–1.28

0.001

1.06

0.91–1.19

0.72

sRANKL per 100 pg/mL

1.08

1.02–1.15

0.001

1.02

0.86–1.07

0.66

sRANKL/osteoprotegerin per 0.15 units

1.56

1.23–1.72

0.002

1.17

1.04–1.25

0.003

Adiponectin per 3.5 μg/mL

1.05

1.01–1.09

0.006

1.03

0.89–1.07

0.54

CD14+CD309+ MPCs per 10 × 10−4%

1.12

1.05–1.27

0.001

1.05

1.00–1.11

0.01

CD14+CD309+Tie2+ MPCs per −0,2 × 10−4%

1.15

1.03–1.29

0.006

1.06

1.01–1.09

0.001

CD31+/annexin V+ EMPs per 0.2 cells/mL

1.18

1.10–1.27

0.001

1.07

1.02–1.13

0.001

CD31+/annexin V+ EMPs to CD14+CD309+ MPCs per 2.5 × 10 units

2.14

1.18–3.55

0.001

1.19

1.12–1.27

0.001

  1. Notes: CI confidence interval, OR odds ration, HbA1c glycated hemoglobin, BNP brain natriuretic peptide, sRANKL serum receptor activator of nuclear factor-kappa B ligand, EMPs endothelial-derived apoptotic microparticles, MPCs mononuclear progenitor cells